Wade W. Chien

Wade W. Chien

Otolaryngology
6420 Rockledge Drive, Suite 4920
Suite 4920
Bethesda, MD 20817

Last Updated: 09/26/2026

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Found 58 publications

Bi-allelic missense variants in human GPN2 result in Perrault syndrome.

Bi-allelic missense variants in human GPN2 result in Perrault syndrome.

Journal: American journal of human genetics
Published: March 27, 2026

The development of inner ear gene therapy for DFNB9: From bench to bedside.

The development of inner ear gene therapy for DFNB9: From bench to bedside.

Journal: Hearing research
Published: December 24, 2025

Predictors of postoperative gustatory disturbance and gustatory recovery following microsurgical resection of vestibular schwannoma.

Predictors of postoperative gustatory disturbance and gustatory recovery following microsurgical resection of vestibular schwannoma.

Journal: Journal of neuro-oncology
Published: November 16, 2025

The relationship between extent of resection, tumor recurrence, and facial nerve outcomes in vestibular schwannoma surgery: a single-institution experience and systematic review.

The relationship between extent of resection, tumor recurrence, and facial nerve outcomes in vestibular schwannoma surgery: a single-institution experience and systematic review.

Journal: Journal of neuro-oncology
Published: September 11, 2025

International expert consensus on gene therapy for hereditary hearing loss: Based on clinical trials.

International expert consensus on gene therapy for hereditary hearing loss: Based on clinical trials.

Journal: Med (New York, N.Y.)
Published: July 22, 2025

The Acoustic Neuroma-7 Score: An Externally Validated Tool Predicting Facial Nerve Outcome After Vestibular Schwannoma Surgery.

The Acoustic Neuroma-7 Score: An Externally Validated Tool Predicting Facial Nerve Outcome After Vestibular Schwannoma Surgery.

Journal: Neurosurgery
Published: July 16, 2025

SLC26A4-AP-2 mu2 interaction regulates SLC26A4 plasma membrane abundance in the endolymphatic sac.

SLC26A4-AP-2 mu2 interaction regulates SLC26A4 plasma membrane abundance in the endolymphatic sac.

Journal: Science advances
Published: October 09, 2024

AAV-mediated inner ear gene delivery triggers mild host immune responses in the mammalian inner ear.

AAV-mediated inner ear gene delivery triggers mild host immune responses in the mammalian inner ear.

Journal: Molecular therapy. Methods & clinical development
Published: September 10, 2024

Interaction between the TBC1D24 TLDc domain and the KIBRA C2 domain is disrupted by two epilepsy-associated TBC1D24 missense variants.

Interaction between the TBC1D24 TLDc domain and the KIBRA C2 domain is disrupted by two epilepsy-associated TBC1D24 missense variants.

Journal: The Journal of biological chemistry
Published: March 27, 2024

Early-Onset Hearing Loss in Mouse Models of Alzheimer's Disease and Increased DNA Damage in the Cochlea.

Early-Onset Hearing Loss in Mouse Models of Alzheimer's Disease and Increased DNA Damage in the Cochlea.

Journal: Aging biology
Published: March 19, 2024

Dual-AAV vector-mediated expression of MYO7A improves vestibular function in a mouse model of Usher syndrome 1B.

Dual-AAV vector-mediated expression of MYO7A improves vestibular function in a mouse model of Usher syndrome 1B.

Journal: Molecular therapy. Methods & clinical development
Published: March 14, 2023

Combined AAV-mediated gene replacement therapy improves auditory function in a mouse model of human DFNB42 deafness.

Combined AAV-mediated gene replacement therapy improves auditory function in a mouse model of human DFNB42 deafness.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: February 08, 2023
Showing 1-12 of 58

Last Updated: 09/26/2026