Wan Y. Ho

Singapore, Singapore

Last Updated: 09/26/2026

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Found 17 publications

FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons.

FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons.

Journal: iScience

Published: August 28, 2023

Central nervous system cholesterol metabolism in health and disease.

Central nervous system cholesterol metabolism in health and disease.

Journal: IUBMB life

Published: November 30, 2021

Cholesterol dyshomeostasis in amyotrophic lateral sclerosis: cause, consequence, or epiphenomenon?

Cholesterol dyshomeostasis in amyotrophic lateral sclerosis: cause, consequence, or epiphenomenon?

Journal: The FEBS journal

Published: July 09, 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Journal: Autophagy

Published: February 26, 2021

Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction.

Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: October 31, 2020

TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells.

TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells.

Journal: eLife

Published: October 29, 2020

Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits.

Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits.

Journal: Acta neuropathologica communications

Published: October 14, 2020

Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesis.

Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesis.

Journal: Acta neuropathologica communications

Published: July 08, 2020

TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.

TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.

Journal: The Journal of cell biology

Published: October 31, 2019

Dedifferentiated endometrioid adenocarcinoma of the uterus: A case series and review of literature.

Dedifferentiated endometrioid adenocarcinoma of the uterus: A case series and review of literature.

Journal: Gynecologic oncology reports

Published: October 22, 2019

The vulnerability of motor and frontal cortex-dependent behaviors in mice expressing ALS-linked mutation in TDP-43.

The vulnerability of motor and frontal cortex-dependent behaviors in mice expressing ALS-linked mutation in TDP-43.

Journal: Neurobiology of aging

Published: September 30, 2019

Elevated FUS levels by overriding its autoregulation produce gain-of-toxicity properties that disrupt protein and RNA homeostasis.

Elevated FUS levels by overriding its autoregulation produce gain-of-toxicity properties that disrupt protein and RNA homeostasis.

Journal: Autophagy

Published: June 25, 2019

Showing 1-12 of 17

Last Updated: 09/26/2026