Wang Wu

Union Hospital
Wuhan, 430022, China

Last Updated: 09/26/2026

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Found 11 publications

Impaired Chaperone-Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation.

Impaired Chaperone-Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: May 21, 2026

A Challenge-Oriented Review of Delivery Systems for Cell and Gene Therapies in Intervertebral Disc Degeneration.

A Challenge-Oriented Review of Delivery Systems for Cell and Gene Therapies in Intervertebral Disc Degeneration.

Journal: Bioengineering (Basel, Switzerland)

Published: April 09, 2026

A sono-piezoelectric scaffold prompts disc regeneration by activating Ca2+/CaMKII/Parkin-mediated mitophagy.

A sono-piezoelectric scaffold prompts disc regeneration by activating Ca2+/CaMKII/Parkin-mediated mitophagy.

Journal: Biomaterials

Published: January 26, 2026

The role of NOTCH signaling pathway in intervertebral disc degeneration.

The role of NOTCH signaling pathway in intervertebral disc degeneration.

Journal: Tissue & cell

Published: November 27, 2025

Microenvironment-educated MSC-EVs loaded injectable smart hydrogel for targeting senescent nucleus pulposus cells and inhibiting ferroptosis against intervertebral disc degeneration.

Microenvironment-educated MSC-EVs loaded injectable smart hydrogel for targeting senescent nucleus pulposus cells and inhibiting ferroptosis against intervertebral disc degeneration.

Journal: Bioactive materials

Published: November 26, 2025

Elevated TRIM25 Impairs Poly (ADP-ribose) Metabolism via PARG Degradation and Mediates Compression-Induced Intervertebral Disc Degeneration.

Elevated TRIM25 Impairs Poly (ADP-ribose) Metabolism via PARG Degradation and Mediates Compression-Induced Intervertebral Disc Degeneration.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: September 29, 2025

Ultrasound-responsive piezoelectric hydrogel attenuates oxidative stress-induced nucleus pulposus senescence via AMPK-FOXO1a-mediated mitophagy for intervertebral disc regeneration.

Ultrasound-responsive piezoelectric hydrogel attenuates oxidative stress-induced nucleus pulposus senescence via AMPK-FOXO1a-mediated mitophagy for intervertebral disc regeneration.

Journal: Biomaterials

Published: July 27, 2025

Pyroptosis: mechanism and therapeutic strategies with intervertebral disc degeneration.

Pyroptosis: mechanism and therapeutic strategies with intervertebral disc degeneration.

Journal: Experimental & molecular medicine

Published: June 19, 2025

Mn-MIL-100@AKG alleviates intervertebral disc degeneration by regulating mitophagy.

Mn-MIL-100@AKG alleviates intervertebral disc degeneration by regulating mitophagy.

Journal: Materials today. Bio

Published: June 01, 2025

Tailorable bimetallic nanozyme mitigates intervertebral disc degeneration by inhibiting oxidative stress and inflammageing.

Tailorable bimetallic nanozyme mitigates intervertebral disc degeneration by inhibiting oxidative stress and inflammageing.

Journal: Theranostics

Published: December 11, 2024

USP5-Rich Apoptotic Extracellular Vesicles Regulate Nucleus Pulposus Cells Apoptosis and DNA Damage Repair by Preventing E2F1 Proteasomal Degradation.

USP5-Rich Apoptotic Extracellular Vesicles Regulate Nucleus Pulposus Cells Apoptosis and DNA Damage Repair by Preventing E2F1 Proteasomal Degradation.

Journal: Journal of extracellular vesicles

Published: December 02, 2024

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Last Updated: 09/26/2026