Weei-chin N. Lin

Hematology | Oncology

1504 Taub Loop
Houston, TX 77030

Last Updated: 09/26/2026

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Found 29 publications

Development of a structurally distinct TopBP1 inhibitor that enhances PARP blockade and reverses osimertinib resistance.

Development of a structurally distinct TopBP1 inhibitor that enhances PARP blockade and reverses osimertinib resistance.

Journal: Science advances

Published: August 05, 2026

Mutant p53 variants differentially impact replication initiation and activate cGAS-STING to affect immune checkpoint inhibition.

Mutant p53 variants differentially impact replication initiation and activate cGAS-STING to affect immune checkpoint inhibition.

Journal: Communications biology

Published: March 31, 2025

A small-molecule inhibitor of TopBP1 exerts anti-MYC activity and synergy with PARP inhibitors.

A small-molecule inhibitor of TopBP1 exerts anti-MYC activity and synergy with PARP inhibitors.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: October 25, 2023

DNA2 Nuclease Inhibition Confers Synthetic Lethality in Cancers with Mutant p53 and Synergizes with PARP Inhibitors.

DNA2 Nuclease Inhibition Confers Synthetic Lethality in Cancers with Mutant p53 and Synergizes with PARP Inhibitors.

Journal: Cancer research communications

Published: April 10, 2023

A novel prediction model of the risk of pancreatic cancer among diabetes patients using multiple clinical data and machine learning.

A novel prediction model of the risk of pancreatic cancer among diabetes patients using multiple clinical data and machine learning.

Journal: Cancer medicine

Published: March 24, 2023

Super-enhanced MARCO variant drives triple-negative breast cancer progression.

Super-enhanced MARCO variant drives triple-negative breast cancer progression.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 05, 2022

14-3-3τ drives estrogen receptor loss via ERα36 induction and GATA3 inhibition in breast cancer.

14-3-3τ drives estrogen receptor loss via ERα36 induction and GATA3 inhibition in breast cancer.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: October 17, 2022

Associations of Warfarin Use with Risks of Ischemic Cerebrovascular Events and Major Bleeding in Patients with Hyperthyroidism-Related Atrial Fibrillation.

Associations of Warfarin Use with Risks of Ischemic Cerebrovascular Events and Major Bleeding in Patients with Hyperthyroidism-Related Atrial Fibrillation.

Journal: Biomedicines

Published: August 24, 2022

Effectiveness and Safety of Immunosuppressants and Biological Therapy for Chronic Spontaneous Urticaria: A Network Meta-Analysis.

Effectiveness and Safety of Immunosuppressants and Biological Therapy for Chronic Spontaneous Urticaria: A Network Meta-Analysis.

Journal: Biomedicines

Published: July 22, 2022

Correction: Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer.

Correction: Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer.

Journal: The Journal of biological chemistry

Published: July 04, 2021

Central nervous system intravascular lymphoma leading to rapidly progressive dementia.

Central nervous system intravascular lymphoma leading to rapidly progressive dementia.

Journal: Proceedings (Baylor University. Medical Center)

Published: May 06, 2021

RNF144A deficiency promotes PD-L1 protein stabilization and carcinogen-induced bladder tumorigenesis.

RNF144A deficiency promotes PD-L1 protein stabilization and carcinogen-induced bladder tumorigenesis.

Journal: Cancer letters

Published: April 07, 2021

Showing 1-12 of 29

Last Updated: 09/26/2026