Weijin Chen

Shandong Key Laboratory Of Druggability Optimization And Evaluation For Lead Compounds
Jinan, 250012, China

Last Updated: 09/26/2026

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Found 10 publications

Novel dual-targeting biofilm inhibitors for potentiating antibiotic efficacy against multidrug-resistant Pseudomonas aeruginosa infections.

Novel dual-targeting biofilm inhibitors for potentiating antibiotic efficacy against multidrug-resistant Pseudomonas aeruginosa infections.

Journal: Journal of advanced research

Published: December 09, 2025

Dipiperazine-Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram-Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes.

Dipiperazine-Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram-Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: July 10, 2025

A novel synthetic method for backbone-cyclized polypeptide POL7080 with the help of hydrophobic-support materials.

A novel synthetic method for backbone-cyclized polypeptide POL7080 with the help of hydrophobic-support materials.

Journal: Organic & biomolecular chemistry

Published: December 04, 2023

Design and Synthesis of 4-Fluorophenyl-5-methylene-2(5H)-furanone Derivatives as Potent Quorum Sensing Inhibitors.

Design and Synthesis of 4-Fluorophenyl-5-methylene-2(5H)-furanone Derivatives as Potent Quorum Sensing Inhibitors.

Journal: Journal of medicinal chemistry

Published: June 13, 2023

Design and synthesis of benzochromene derivatives as AcrB inhibitors for the reversal of bacterial multidrug resistance.

Design and synthesis of benzochromene derivatives as AcrB inhibitors for the reversal of bacterial multidrug resistance.

Journal: European journal of medicinal chemistry

Published: December 08, 2022

Design, synthesis and evaluation of oxazolopyridinone derivatives as quorum sensing inhibitors.

Design, synthesis and evaluation of oxazolopyridinone derivatives as quorum sensing inhibitors.

Journal: Bioorganic chemistry

Published: September 14, 2022

Acridinium-conjugated aromatic heterocycles as highly potent FtsZ inhibitors: Design, synthesis, and biological evaluation.

Acridinium-conjugated aromatic heterocycles as highly potent FtsZ inhibitors: Design, synthesis, and biological evaluation.

Journal: Archiv der Pharmazie

Published: October 13, 2021

Rational design and synthesis of Oreoch-2 analogues as efficient broad-spectrum antimicrobial peptides.

Rational design and synthesis of Oreoch-2 analogues as efficient broad-spectrum antimicrobial peptides.

Journal: Bioorganic chemistry

Published: September 27, 2021

Modification of 5-methylphenanthridium from benzothiazoles to indoles as potent FtsZ inhibitors: Broadening the antibacterial spectrum toward vancomycin-resistant enterococci.

Modification of 5-methylphenanthridium from benzothiazoles to indoles as potent FtsZ inhibitors: Broadening the antibacterial spectrum toward vancomycin-resistant enterococci.

Journal: European journal of medicinal chemistry

Published: May 23, 2021

Design, synthesis and evaluation of novel 9-arylalkyl-10-methylacridinium derivatives as highly potent FtsZ-targeting antibacterial agents.

Design, synthesis and evaluation of novel 9-arylalkyl-10-methylacridinium derivatives as highly potent FtsZ-targeting antibacterial agents.

Journal: European journal of medicinal chemistry

Published: March 26, 2021

Showing 1-10 of 10

Last Updated: 09/26/2026