Weikai Ge

Guangzhou, 510530, China

Last Updated: 09/26/2026

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Found 14 publications

Development of mitochondrial mutator pigs exhibiting increased mitochondrial DNA mutations and premature aging via prime editing.

Development of mitochondrial mutator pigs exhibiting increased mitochondrial DNA mutations and premature aging via prime editing.

Journal: Science advances

Published: August 26, 2026

In vivo evaluation of guide-free Cas9-induced safety risks in a pig model.

In vivo evaluation of guide-free Cas9-induced safety risks in a pig model.

Journal: Signal transduction and targeted therapy

Published: September 14, 2023

Evaluation of guide-free Cas9-induced genomic damage and transcriptome changes in pig embryos.

Evaluation of guide-free Cas9-induced genomic damage and transcriptome changes in pig embryos.

Journal: Molecular therapy. Nucleic acids

Published: February 08, 2023

Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation.

Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation.

Journal: Genome biology

Published: May 05, 2022

Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression.

Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression.

Journal: Science China. Life sciences

Published: November 05, 2021

AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns.

AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns.

Journal: Nucleic acids research

Published: November 01, 2021

Correction: Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses.

Correction: Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: September 28, 2021

ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems.

ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems.

Journal: BMC biology

Published: April 01, 2020

CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I.

CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: February 12, 2020

Improving the Cpf1-mediated base editing system by combining dCas9/dead sgRNA with human APOBEC3A variants.

Improving the Cpf1-mediated base editing system by combining dCas9/dead sgRNA with human APOBEC3A variants.

Journal: Journal of genetics and genomics = Yi chuan xue bao

Published: January 21, 2020

Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses.

Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: December 12, 2019

Efficient base editing for multiple genes and loci in pigs using base editors.

Efficient base editing for multiple genes and loci in pigs using base editors.

Journal: Nature communications

Published: October 21, 2018

Showing 1-12 of 14

Last Updated: 09/26/2026