Weiqiang X. Lu

500 Dongchuan Road
Shanghai, 200241, China

Last Updated: 09/26/2026

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Found 93 publications

Discovery and Characterization of Benzamide Derivatives as Highly Potent SUCNR1 Antagonists for Cancer Immunotherapy.

Discovery and Characterization of Benzamide Derivatives as Highly Potent SUCNR1 Antagonists for Cancer Immunotherapy.

Journal: Journal of medicinal chemistry
Published: May 08, 2026

Discovery of 1,2,3,4-Tetrahydrochromeno[3,4-c]pyridin-5-one Derivatives as Novel MTHFD Inhibitors for the Treatment of Acute Myeloid Leukemia.

Discovery of 1,2,3,4-Tetrahydrochromeno[3,4-c]pyridin-5-one Derivatives as Novel MTHFD Inhibitors for the Treatment of Acute Myeloid Leukemia.

Journal: Journal of medicinal chemistry
Published: March 20, 2026

DHODH is a synthetic lethal target in PIK3CA-mutant colorectal cancer.

DHODH is a synthetic lethal target in PIK3CA-mutant colorectal cancer.

Journal: Cell reports
Published: January 29, 2026

Author Correction: PPIA dictates NRF2 stability to promote lung cancer progression.

Author Correction: PPIA dictates NRF2 stability to promote lung cancer progression.

Journal: Nature communications
Published: December 15, 2025

Structural mechanisms for self-activation of protease-activated receptor 4 by tethered ligand.

Structural mechanisms for self-activation of protease-activated receptor 4 by tethered ligand.

Journal: Cell reports
Published: November 10, 2025

Target-Centric Multiplexed Screening of an Herbal Extract Identifies a Novel Dual A2A/A2B Receptor Antagonist for Cancer Immunotherapy.

Target-Centric Multiplexed Screening of an Herbal Extract Identifies a Novel Dual A2A/A2B Receptor Antagonist for Cancer Immunotherapy.

Journal: ACS central science
Published: October 13, 2025

Targeting EP2/EP4-driven expansion of suppressive VSIG4high macrophages overcomes immunotherapy resistance in colorectal cancer.

Targeting EP2/EP4-driven expansion of suppressive VSIG4high macrophages overcomes immunotherapy resistance in colorectal cancer.

Journal: Cell reports
Published: September 13, 2025

Author Correction: The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer.

Author Correction: The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer.

Journal: Nature immunology
Published: March 11, 2025

Exercise increases bone mass by lactate/Gpr81 signaling pathway.

Exercise increases bone mass by lactate/Gpr81 signaling pathway.

Journal: Communications biology
Published: March 03, 2025

Subtle Structural Modifications Spanning from EP4 Antagonism to EP2/EP4 Dual Antagonism: A Novel Class of Thienocyclic-Based Derivatives.

Subtle Structural Modifications Spanning from EP4 Antagonism to EP2/EP4 Dual Antagonism: A Novel Class of Thienocyclic-Based Derivatives.

Journal: Journal of medicinal chemistry
Published: January 06, 2025

Design, synthesis, and biological evaluations of 5-aryl-pyrazole-3-carboxamide derivatives as selective CB2 receptor agonists for the treatment of colitis.

Design, synthesis, and biological evaluations of 5-aryl-pyrazole-3-carboxamide derivatives as selective CB2 receptor agonists for the treatment of colitis.

Journal: European journal of medicinal chemistry
Published: October 09, 2024

Cryo-EM structure of an activated GPR4-Gs signaling complex.

Cryo-EM structure of an activated GPR4-Gs signaling complex.

Journal: Nature communications
Published: June 05, 2024
Showing 1-12 of 93

Last Updated: 09/26/2026