Wen J. Hu - Publications

Structural basis of β-arrestin coupling and transducer selectivity in PAC1R.

Journal: Acta pharmacologica Sinica

Published: June 24, 2026

Structural basis for lysophosphatidic acid recognition and atypical Gαq coupling by LPAR5.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: June 18, 2026

Risk factor analysis and nomogram predictive model construction for neonatal hypospadias: a large-scale multicenter study in East China.

Journal: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Published: April 27, 2026

Structural basis for dual targeting of μ-opioid and nociceptin/orphanin FQ receptors by Cebranopadol.

Journal: Acta pharmacologica Sinica

Published: March 05, 2026

Effect of modified Mediterranean diet supplemented with partial enteral nutrition in post-surgical patients with Crohn's disease: a pilot clinical trial.

Journal: The British journal of nutrition

Published: February 27, 2026

Structure-based design of an opioid receptor modulator for enhanced morphine analgesia.

Journal: Science advances

Published: February 11, 2026

Anther middle layer fatty acid synthesis is essential for pollen development and fertility restoration at low temperature in Arabidopsis.

Journal: Plant physiology

Published: February 08, 2026

Structural insights into nonpeptide antagonist inhibition of somatostatin receptor subtype 5.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 19, 2025

Cryo-EM structures of GPR75 reveal an occluded orthosteric pocket challenging conventional drug discovery paradigms for an anti-obesity target.

Journal: Acta pharmacologica Sinica

Published: October 26, 2025

Molecular architecture of OXGR1 reveals an evolutionary conserved mechanisms for metabolite surveillance.

Journal: The EMBO journal

Published: September 28, 2025

Rational design of a Kappa opioid receptor peptide agonist with attenuated β-arrestin signaling.

Journal: Nature communications

Published: September 09, 2025

Structural Pharmacology of Bufotenine Derivatives in Activating the 5-HT1A Receptor for Therapeutic Potential in Depression and Anxiety.

Journal: Research (Washington, D.C.)

Published: August 17, 2025