Wen Li

State Key Laboratory Of Genetic Engineering And MOE Key Laboratory Of Contemporary Anthropology, 200032, PR China Institute Of Biomedical Sciences, No 138 Yixueyuan Road, 200032, PR China
Shanghai, Puerto Rico

Last Updated: 09/26/2026

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Found 11 publications

Design, synthesis, and antibacterial activity study of novel β - aminoketone compounds based on the symmetrical twin-drugs design method.

Design, synthesis, and antibacterial activity study of novel β - aminoketone compounds based on the symmetrical twin-drugs design method.

Journal: European journal of medicinal chemistry

Published: February 14, 2026

From local anesthetics to antibacterial agents: design, synthesis, and activity evaluation of dyclonine quaternary ammonium salt derivatives.

From local anesthetics to antibacterial agents: design, synthesis, and activity evaluation of dyclonine quaternary ammonium salt derivatives.

Journal: Bioorganic chemistry

Published: January 30, 2026

Fisetin-loaded nanoparticles as a novel approach for cholesterol regulation in hypercholesterolemia: targeting the ASGR1-mediated mTORC1/AMPK pathway.

Fisetin-loaded nanoparticles as a novel approach for cholesterol regulation in hypercholesterolemia: targeting the ASGR1-mediated mTORC1/AMPK pathway.

Journal: Journal of nanobiotechnology

Published: November 10, 2025

Inhibition of Protein arginine methyltransferase 6 reduces reactive oxygen species production and attenuates aminoglycoside- and cisplatin-induced hair cell death.

Inhibition of Protein arginine methyltransferase 6 reduces reactive oxygen species production and attenuates aminoglycoside- and cisplatin-induced hair cell death.

Journal: Theranostics

Published: June 06, 2019

Identifying the novel inhibitors of lysine-specific demethylase 1 (LSD1) combining pharmacophore-based and structure-based virtual screening.

Identifying the novel inhibitors of lysine-specific demethylase 1 (LSD1) combining pharmacophore-based and structure-based virtual screening.

Journal: Journal of biomolecular structure & dynamics

Published: October 28, 2018

3D-QSAR (CoMFA, CoMSIA), molecular docking and molecular dynamics simulations study of 6-aryl-5-cyano-pyrimidine derivatives to explore the structure requirements of LSD1 inhibitors.

3D-QSAR (CoMFA, CoMSIA), molecular docking and molecular dynamics simulations study of 6-aryl-5-cyano-pyrimidine derivatives to explore the structure requirements of LSD1 inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: February 02, 2017

ILDR1 deficiency causes degeneration of cochlear outer hair cells and disrupts the structure of the organ of Corti: a mouse model for human DFNB42.

ILDR1 deficiency causes degeneration of cochlear outer hair cells and disrupts the structure of the organ of Corti: a mouse model for human DFNB42.

Journal: Biology open

Published: March 31, 2015

A metabolic profiling analysis of the acute toxicological effects of the realgar (As₂S₂) combined with other herbs in Niuhuang Jiedu Tablet using ¹H NMR spectroscopy.

A metabolic profiling analysis of the acute toxicological effects of the realgar (As₂S₂) combined with other herbs in Niuhuang Jiedu Tablet using ¹H NMR spectroscopy.

Journal: Journal of ethnopharmacology

Published: October 18, 2013

(1)H NMR-based metabonomics study on the toxicity alleviation effect of other traditional Chinese medicines in Niuhuang Jiedu tablet to realgar (As2S2).

(1)H NMR-based metabonomics study on the toxicity alleviation effect of other traditional Chinese medicines in Niuhuang Jiedu tablet to realgar (As2S2).

Journal: Journal of ethnopharmacology

Published: October 23, 2012

Recent advances in the structure-activity relationship study of small-molecule sodium channel blockers with analgesic effects

Recent advances in the structure-activity relationship study of small-molecule sodium channel blockers with analgesic effects

Journal: Yao xue xue bao = Acta pharmaceutica Sinica

Published: May 05, 2009

Synthesis and local anesthetic activity of fluoro-substituted imipramine and its analogues.

Synthesis and local anesthetic activity of fluoro-substituted imipramine and its analogues.

Journal: Bioorganic & medicinal chemistry letters

Published: December 02, 2006

Showing 1-11 of 11

Last Updated: 09/26/2026