Wen Zhang
Macau, China
Last Updated: 09/26/2026
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Found 10 publications
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics.
Journal: ACS combinatorial science
Published: October 24, 2018
Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors.
Journal: Journal of proteome research
Published: July 21, 2018
Pharmacological synergism of 2,2-dichloroacetophenone and EGFR-TKi to overcome TKi-induced resistance in NSCLC cells.
Journal: European journal of pharmacology
Published: June 21, 2017
Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti-cancer effect.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Published: February 28, 2017
Synthesis and biological evaluation of (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Published: January 13, 2017
Unexpected Discovery of Dichloroacetate Derived Adenosine Triphosphate Competitors Targeting Pyruvate Dehydrogenase Kinase To Inhibit Cancer Proliferation.
Journal: Journal of medicinal chemistry
Published: March 24, 2016
Targeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target?
Journal: International journal of biological sciences
Published: July 23, 2015
Development of pyruvate dehydrogenase kinase inhibitors in medicinal chemistry with particular emphasis as anticancer agents.
Journal: Drug discovery today
Published: January 26, 2015
Predicting the human jejunal permeability and fraction absorbed of fluoroquinolones based on a biophysical model.
Journal: Bio-medical materials and engineering
Published: September 18, 2014
Predicting the minimal inhibitory concentration of fluoroquinolones for Escherichia coli using an accumulation model.
Journal: Bio-medical materials and engineering
Published: September 18, 2014
Showing 1-10 of 10
Last Updated: 09/26/2026