Wenchen Pu

State Key Laboratory Of Biotherapy And Cancer Center
Chengdu, 610041, China

Last Updated: 09/26/2026

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Found 38 publications

Correction: Circular RNA F-circSR derived from SLC34A2-ROS1 fusion gene promotes cell migration in non-small cell lung cancer.

Correction: Circular RNA F-circSR derived from SLC34A2-ROS1 fusion gene promotes cell migration in non-small cell lung cancer.

Journal: Molecular cancer
Published: May 01, 2026

Discovery of a Novel G9a-Selective Inhibitor for Hepatocellular Carcinoma Treatment.

Discovery of a Novel G9a-Selective Inhibitor for Hepatocellular Carcinoma Treatment.

Journal: ACS medicinal chemistry letters
Published: July 24, 2025

Optimization of 1-Methyl-3-(pyridin-3-yl)-1H-indol Derivatives as ROR1 Inhibitors with Improved Activity and Selectivity.

Optimization of 1-Methyl-3-(pyridin-3-yl)-1H-indol Derivatives as ROR1 Inhibitors with Improved Activity and Selectivity.

Journal: Journal of medicinal chemistry
Published: June 02, 2025

Structure-directing optimization of N-(2,3-dihydrobenzo[b] [1,4]dioxin-6-yl)benzamide derivatives as selective receptor tyrosine kinase-like orphan receptor 1 (ROR1) inhibitors for cancer therapy.

Structure-directing optimization of N-(2,3-dihydrobenzo[b] [1,4]dioxin-6-yl)benzamide derivatives as selective receptor tyrosine kinase-like orphan receptor 1 (ROR1) inhibitors for cancer therapy.

Journal: European journal of medicinal chemistry
Published: March 25, 2025

Antibody-based targeted protein degradation for membrane and extracellular proteins: emerging strategies and breakthroughs.

Antibody-based targeted protein degradation for membrane and extracellular proteins: emerging strategies and breakthroughs.

Journal: Science China. Life sciences
Published: March 02, 2025

Rational Design, Synthesis, and Biological Evaluation of Novel c-Met Degraders for Lung Cancer Therapy.

Rational Design, Synthesis, and Biological Evaluation of Novel c-Met Degraders for Lung Cancer Therapy.

Journal: Journal of medicinal chemistry
Published: January 30, 2025

Structure-Guided Optimization and Preclinical Evaluation of 6-O-Benzylguanine-Based Pin1 Inhibitor for Hepatocellular Carcinoma Treatment.

Structure-Guided Optimization and Preclinical Evaluation of 6-O-Benzylguanine-Based Pin1 Inhibitor for Hepatocellular Carcinoma Treatment.

Journal: Journal of medicinal chemistry
Published: January 27, 2025

Targeting oncogenic transcriptional factor c-myc by oligonucleotide PROTAC for the treatment of hepatocellular carcinoma.

Targeting oncogenic transcriptional factor c-myc by oligonucleotide PROTAC for the treatment of hepatocellular carcinoma.

Journal: European journal of medicinal chemistry
Published: September 02, 2024

Penfluridol inhibits melanoma growth and metastasis through enhancing von Hippel‒Lindau tumor suppressor-mediated cancerous inhibitor of protein phosphatase 2A (CIP2A) degradation.

Penfluridol inhibits melanoma growth and metastasis through enhancing von Hippel‒Lindau tumor suppressor-mediated cancerous inhibitor of protein phosphatase 2A (CIP2A) degradation.

Journal: MedComm
Published: August 08, 2024

The tumor-intrinsic role of the m6A reader YTHDF2 in regulating immune evasion.

The tumor-intrinsic role of the m6A reader YTHDF2 in regulating immune evasion.

Journal: Science immunology
Published: May 31, 2024

Small-molecule-based targeted therapy in liver cancer.

Small-molecule-based targeted therapy in liver cancer.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: November 22, 2023

Exosomes rewire the cartilage microenvironment in osteoarthritis: from intercellular communication to therapeutic strategies.

Exosomes rewire the cartilage microenvironment in osteoarthritis: from intercellular communication to therapeutic strategies.

Journal: International journal of oral science
Published: April 19, 2022
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Last Updated: 09/26/2026