Wenchong Tan

Guangzhou, 510006, China

Last Updated: 09/26/2026

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Found 12 publications

Structure-Based Virtual Screening Discovers Potent PLK1 Inhibitors with Anticancer Activity.

Structure-Based Virtual Screening Discovers Potent PLK1 Inhibitors with Anticancer Activity.

Journal: Journal of chemical information and modeling

Published: January 06, 2026

Comprehensive Drug-Likeness Prediction Using a Pretrained Transformer Model and Multitask Learning.

Comprehensive Drug-Likeness Prediction Using a Pretrained Transformer Model and Multitask Learning.

Journal: Journal of chemical information and modeling

Published: May 20, 2025

Hsp90 C-terminal domain inhibition enhances ferroptosis by disrupting GPX4-VDAC1 interaction to increase HMOX1 release from oligomerized VDAC1 channels.

Hsp90 C-terminal domain inhibition enhances ferroptosis by disrupting GPX4-VDAC1 interaction to increase HMOX1 release from oligomerized VDAC1 channels.

Journal: Redox biology

Published: May 02, 2025

ENsiRNA: A Multimodality Method for siRNA-mRNA and Modified siRNA Efficacy Prediction Based on Geometric Graph Neural Network.

ENsiRNA: A Multimodality Method for siRNA-mRNA and Modified siRNA Efficacy Prediction Based on Geometric Graph Neural Network.

Journal: Journal of molecular biology

Published: November 12, 2024

NeoaPred: a deep-learning framework for predicting immunogenic neoantigen based on surface and structural features of peptide-human leukocyte antigen complexes.

NeoaPred: a deep-learning framework for predicting immunogenic neoantigen based on surface and structural features of peptide-human leukocyte antigen complexes.

Journal: Bioinformatics (Oxford, England)

Published: April 01, 2024

Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma.

Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma.

Journal: Journal of lipid research

Published: March 22, 2024

Human epididymis protein 4, a novel potential biomarker for diagnostic and prognosis monitoring of lung cancer.

Human epididymis protein 4, a novel potential biomarker for diagnostic and prognosis monitoring of lung cancer.

Journal: The clinical respiratory journal

Published: January 10, 2024

HSP90 C-terminal domain inhibition promotes VDAC1 oligomerization via decreasing K274 mono-ubiquitination in Hepatocellular Carcinoma.

HSP90 C-terminal domain inhibition promotes VDAC1 oligomerization via decreasing K274 mono-ubiquitination in Hepatocellular Carcinoma.

Journal: Neoplasia (New York, N.Y.)

Published: July 14, 2023

Hsp90 Inhibitor STA9090 induced VPS35 related extracellular vesicle release and metastasis in hepatocellular carcinoma.

Hsp90 Inhibitor STA9090 induced VPS35 related extracellular vesicle release and metastasis in hepatocellular carcinoma.

Journal: Translational oncology

Published: June 24, 2022

Extracellular Hsp90α, which participates in vascular inflammation, is a novel serum predictor of atherosclerosis in type 2 diabetes.

Extracellular Hsp90α, which participates in vascular inflammation, is a novel serum predictor of atherosclerosis in type 2 diabetes.

Journal: BMJ open diabetes research & care

Published: August 31, 2021

Hsp90 Inhibitor STA9090 Sensitizes Hepatocellular Carcinoma to Hyperthermia-Induced DNA Damage by Suppressing DNA-PKcs Protein Stability and mRNA Transcription.

Hsp90 Inhibitor STA9090 Sensitizes Hepatocellular Carcinoma to Hyperthermia-Induced DNA Damage by Suppressing DNA-PKcs Protein Stability and mRNA Transcription.

Journal: Molecular cancer therapeutics

Published: March 08, 2021

Bclaf1 promotes angiogenesis by regulating HIF-1α transcription in hepatocellular carcinoma.

Bclaf1 promotes angiogenesis by regulating HIF-1α transcription in hepatocellular carcinoma.

Journal: Oncogene

Published: July 23, 2018

Showing 1-12 of 12

Last Updated: 09/26/2026