Wendong Guo

Key Laboratory Of Medical Cell Biology, Key Laboratory Of Liaoning Province
Shenyang, 110122, China

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 21 publications

Enhanced insulin signaling via circulating ATG7: A potential therapeutic strategy for diabetes.

Enhanced insulin signaling via circulating ATG7: A potential therapeutic strategy for diabetes.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 29, 2025

The p53 R181C mutation accumulates through impaired deacetylation by Sirt1 and facilitates tumor development.

The p53 R181C mutation accumulates through impaired deacetylation by Sirt1 and facilitates tumor development.

Journal: Communications biology

Published: December 16, 2024

The deacetylase SIRT6 reduces amyloid pathology and supports cognition in mice by reducing the stability of APP in neurons.

The deacetylase SIRT6 reduces amyloid pathology and supports cognition in mice by reducing the stability of APP in neurons.

Journal: Science signaling

Published: December 10, 2024

Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response.

Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response.

Journal: Cell reports

Published: May 15, 2024

Insights on E1-like enzyme ATG7: functional regulation and relationships with aging-related diseases.

Insights on E1-like enzyme ATG7: functional regulation and relationships with aging-related diseases.

Journal: Communications biology

Published: November 19, 2023

A novel role for the ROS-ATM-Chk2 axis mediated metabolic and cell cycle reprogramming in the M1 macrophage polarization.

A novel role for the ROS-ATM-Chk2 axis mediated metabolic and cell cycle reprogramming in the M1 macrophage polarization.

Journal: Redox biology

Published: October 19, 2023

Atg7 senses ATP levels and regulates AKT1-PDCD4 phosphorylation-ubiquitination axis to promote survival during metabolic stress.

Atg7 senses ATP levels and regulates AKT1-PDCD4 phosphorylation-ubiquitination axis to promote survival during metabolic stress.

Journal: Communications biology

Published: June 26, 2023

Regulated secretion of mutant p53 negatively affects T lymphocytes in the tumor microenvironment.

Regulated secretion of mutant p53 negatively affects T lymphocytes in the tumor microenvironment.

Journal: Oncogene

Published: April 12, 2023

Cooperative effects of SIRT1 and SIRT2 on APP acetylation.

Cooperative effects of SIRT1 and SIRT2 on APP acetylation.

Journal: Aging cell

Published: February 28, 2023

De-ubiquitination of SAMHD1 by USP7 promotes DNA damage repair to overcome oncogenic stress and affect chemotherapy sensitivity.

De-ubiquitination of SAMHD1 by USP7 promotes DNA damage repair to overcome oncogenic stress and affect chemotherapy sensitivity.

Journal: Oncogene

Published: August 12, 2022

Progerin modulates the IGF-1R/Akt signaling involved in aging.

Progerin modulates the IGF-1R/Akt signaling involved in aging.

Journal: Science advances

Published: July 20, 2022

Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice.

Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice.

Journal: Cell reports

Published: November 17, 2021

Showing 1-12 of 21

Last Updated: 09/26/2026