Wenhu X. Duan - Publications

The role of Th17/Treg imbalance in the pathogenesis and progression of pneumoconiosis and its clinical implications

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

Published: July 31, 2026

Design, synthesis and pharmacological evaluation of 3H-spiro[benzofuran-2,4'-piperidine] IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma.

Journal: RSC medicinal chemistry

Published: January 12, 2026

Discovery and optimization of 1H-pyrazolo[3,4-d]pyrimidine-3-carboxamide derivatives as USP1 inhibitors for BRCA1-mutant cancer treatment.

Journal: Bioorganic chemistry

Published: January 06, 2026

Discovery of the thieno[2,3-b][1,4]thiazin-2(3H)-one STING inhibitors.

Journal: Bioorganic & medicinal chemistry

Published: December 08, 2025

Discovery of isoindoline-2(1H)-carboxamide STING inhibitors as anti-inflammatory agents.

Journal: Molecular diversity

Published: October 17, 2025

Discovery of a potent and orally bioavailable 3,3-dimethyl-2-oxoindoline STING inhibitor.

Journal: European journal of medicinal chemistry

Published: July 15, 2025

Discovery of 3,4-dihydroisoquinoline-2(1H)-carboxamide STING inhibitors as anti-inflammatory agents.

Journal: European journal of medicinal chemistry

Published: April 28, 2025

Dual targeting of VEGFR2 and CSF1R with SYHA1813 confers novel strategy for treating both BRAF wild-type and mutant melanoma.

Journal: Cancer cell international

Published: March 31, 2025

Discovery of indole derivatives as STING degraders.

Journal: European journal of medicinal chemistry

Published: March 08, 2025

Design, synthesis, and biological evaluation of RIPK1-targeting PROTACs.

Journal: Molecular diversity

Published: January 21, 2025

Incorporation of a rigid 1,3-diketone-containing fragment led to significantly improved AXL inhibitory activity: design, synthesis, and SAR of the anilinopyrimidine AXL inhibitors.

Journal: Molecular diversity

Published: October 25, 2024

Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors.

Journal: Archiv der Pharmazie

Published: July 20, 2024