Wenjie Liu

Shenyang, 110819, China

Last Updated: 09/26/2026

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Found 17 publications

Novel β-Carboline Derivative ZLWH-67 Exerts Potent Anti-MRSA Activity through Multiple Mechanisms.

Novel β-Carboline Derivative ZLWH-67 Exerts Potent Anti-MRSA Activity through Multiple Mechanisms.

Journal: ACS infectious diseases

Published: March 06, 2026

Fluorocyclopropyl-Containing Tacrine Derivatives as Potent and Selective Dual CDK2/CDK9 Inhibitors for the Treatment of Colorectal Cancer.

Fluorocyclopropyl-Containing Tacrine Derivatives as Potent and Selective Dual CDK2/CDK9 Inhibitors for the Treatment of Colorectal Cancer.

Journal: Journal of medicinal chemistry

Published: November 15, 2025

Harmine Derivatives Alleviate LPS-Induced Acute Lung Injury via Targeting GSK3β.

Harmine Derivatives Alleviate LPS-Induced Acute Lung Injury via Targeting GSK3β.

Journal: Inflammation

Published: September 15, 2025

Corrigendum to "Development and structure-activity relationship of tacrine derivatives as highly potent CDK2/9 inhibitors for the treatment of cancer" [Eur. J. Med. Chem. 242 (2022): 114701].

Corrigendum to "Development and structure-activity relationship of tacrine derivatives as highly potent CDK2/9 inhibitors for the treatment of cancer" [Eur. J. Med. Chem. 242 (2022): 114701].

Journal: European journal of medicinal chemistry

Published: July 21, 2025

Harmine derivative ZLWH-38 ameliorates the therapeutic efficacy of colistin against XDR-Ab pneumonia by suppressing inflammatory responses.

Harmine derivative ZLWH-38 ameliorates the therapeutic efficacy of colistin against XDR-Ab pneumonia by suppressing inflammatory responses.

Journal: International immunopharmacology

Published: June 12, 2025

Design, synthesis, and antitumor activity study of β-carboline derivatives as selective HDAC1/2 inhibitors.

Design, synthesis, and antitumor activity study of β-carboline derivatives as selective HDAC1/2 inhibitors.

Journal: Bioorganic chemistry

Published: April 24, 2025

UCP1-inspired mitochondrial uncouplers: Design, synthesis and thermogenic activity studies.

UCP1-inspired mitochondrial uncouplers: Design, synthesis and thermogenic activity studies.

Journal: Bioorganic chemistry

Published: December 05, 2024

Discovery of ZJCK-6-46: A Potent, Selective, and Orally Available Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A Inhibitor for the Treatment of Alzheimer's Disease.

Discovery of ZJCK-6-46: A Potent, Selective, and Orally Available Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A Inhibitor for the Treatment of Alzheimer's Disease.

Journal: Journal of medicinal chemistry

Published: July 23, 2024

Discovery of novel harmine derivatives as GSK-3β/DYRK1A dual inhibitors for Alzheimer's disease treatment.

Discovery of novel harmine derivatives as GSK-3β/DYRK1A dual inhibitors for Alzheimer's disease treatment.

Journal: Archiv der Pharmazie

Published: July 26, 2023

Discovery of novel β-carboline-1,2,3-triazole hybrids as AChE/GSK-3β dual inhibitors for Alzheimer's disease treatment.

Discovery of novel β-carboline-1,2,3-triazole hybrids as AChE/GSK-3β dual inhibitors for Alzheimer's disease treatment.

Journal: Bioorganic chemistry

Published: July 25, 2022

Development and structure-activity relationship of tacrine derivatives as highly potent CDK2/9 inhibitors for the treatment of cancer.

Development and structure-activity relationship of tacrine derivatives as highly potent CDK2/9 inhibitors for the treatment of cancer.

Journal: European journal of medicinal chemistry

Published: June 29, 2022

Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease.

Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease.

Journal: European journal of medicinal chemistry

Published: May 30, 2022

Showing 1-12 of 17

Last Updated: 09/26/2026