Wenle H. Yang

Key Laboratory Of Preclinical Study For New Drugs Of Gansu Province, 2019RU066
Lanzhou, 730000, China

Last Updated: 09/26/2026

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Found 24 publications

All-Hydrocarbon Stapling and Amino Acid Substitution-Modified Antimicrobial Peptide Feleucin-K3 Analogs Enhanced the Stability and Optimized the Therapeutic Index against Multidrug-Resistant Bacteria.

All-Hydrocarbon Stapling and Amino Acid Substitution-Modified Antimicrobial Peptide Feleucin-K3 Analogs Enhanced the Stability and Optimized the Therapeutic Index against Multidrug-Resistant Bacteria.

Journal: Journal of medicinal chemistry

Published: June 09, 2026

Postmodification of Daptomycin at Tryptophan Enables the Discovery of Aryl-Daptomycin Antibiofilm Activity against MRSA.

Postmodification of Daptomycin at Tryptophan Enables the Discovery of Aryl-Daptomycin Antibiofilm Activity against MRSA.

Journal: Journal of medicinal chemistry

Published: May 26, 2026

Cyclization-Based Optimization of the Antimicrobial Peptide YD Yields a Nanomolar Inhibitor of Pulmonary Fibrosis.

Cyclization-Based Optimization of the Antimicrobial Peptide YD Yields a Nanomolar Inhibitor of Pulmonary Fibrosis.

Journal: Journal of medicinal chemistry

Published: March 13, 2026

Halogenated Sulfono-γ-AApeptides Modified Cationic AMPs Have Enhanced Stability and Therapeutic Potential against Clinically Important MDR Infections.

Halogenated Sulfono-γ-AApeptides Modified Cationic AMPs Have Enhanced Stability and Therapeutic Potential against Clinically Important MDR Infections.

Journal: ACS infectious diseases

Published: June 12, 2025

Rational two-round modification for developing isopeptide bond-containing antimicrobial peptide with enhanced stability and potent activity against multidrug-resistant gram-negative bacteria.

Rational two-round modification for developing isopeptide bond-containing antimicrobial peptide with enhanced stability and potent activity against multidrug-resistant gram-negative bacteria.

Journal: Biochemical pharmacology

Published: June 04, 2025

Iterative Optimization Yields Stapled Peptides with Superior Pharmacokinetics and Potency for Renal Fibrosis Treatment.

Iterative Optimization Yields Stapled Peptides with Superior Pharmacokinetics and Potency for Renal Fibrosis Treatment.

Journal: Journal of medicinal chemistry

Published: April 08, 2025

The novel peptide PEP-Z-2 potentially treats renal fibrosis in vivo and in vitro by regulating TGF-β/Smad/AKT/MAPK signaling.

The novel peptide PEP-Z-2 potentially treats renal fibrosis in vivo and in vitro by regulating TGF-β/Smad/AKT/MAPK signaling.

Journal: European journal of pharmacology

Published: May 21, 2024

Enhancing the stability and therapeutic potential of the antimicrobial peptide Feleucin-K3 against Multidrug-Resistant a. Baumannii through rational utilization of a D-amino acid substitution strategy.

Enhancing the stability and therapeutic potential of the antimicrobial peptide Feleucin-K3 against Multidrug-Resistant a. Baumannii through rational utilization of a D-amino acid substitution strategy.

Journal: Biochemical pharmacology

Published: January 24, 2024

Novel Peptide DR3penA as a Low-Toxicity Antirenal Fibrosis Agent by Suppressing the TGF-β1/miR-212-5p/Low-Density Lipoprotein Receptor Class a Domain Containing 4/Smad Axis.

Novel Peptide DR3penA as a Low-Toxicity Antirenal Fibrosis Agent by Suppressing the TGF-β1/miR-212-5p/Low-Density Lipoprotein Receptor Class a Domain Containing 4/Smad Axis.

Journal: ACS pharmacology & translational science

Published: January 11, 2024

Emerging trends of invasive yeast infections and azole resistance in Beijing intensive care units.

Emerging trends of invasive yeast infections and azole resistance in Beijing intensive care units.

Journal: The Journal of hospital infection

Published: January 05, 2024

Novel antimicrobial peptides modified with fluorinated sulfono-γ-AA having high stability and targeting multidrug-resistant bacteria infections.

Novel antimicrobial peptides modified with fluorinated sulfono-γ-AA having high stability and targeting multidrug-resistant bacteria infections.

Journal: European journal of medicinal chemistry

Published: September 11, 2023

The Peptide DHα-(4-pentenyl)-ANPQIR-NH2 Exhibits Antifibrotic Activity in Multiple Pulmonary Fibrosis Models Induced by Particulate and Soluble Chemical Fibrogenic Agents.

The Peptide DHα-(4-pentenyl)-ANPQIR-NH2 Exhibits Antifibrotic Activity in Multiple Pulmonary Fibrosis Models Induced by Particulate and Soluble Chemical Fibrogenic Agents.

Journal: The Journal of pharmacology and experimental therapeutics

Published: July 24, 2023

Showing 1-12 of 24

Last Updated: 09/26/2026