Wenxin Yan

State Key Laboratory Of Natural Medicines
Nanjing, 210009, China

Last Updated: 09/26/2026

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Found 15 publications

Design, synthesis, and biological evaluation of novel brain-penetrant PARP7 inhibitors for the treatment of ischemic stroke.

Design, synthesis, and biological evaluation of novel brain-penetrant PARP7 inhibitors for the treatment of ischemic stroke.

Journal: European journal of medicinal chemistry

Published: May 21, 2026

Correction to "Discovery of Hydroxamic Acid Ester Derivatives as Second-Generation PRMT5 Inhibitors for the Treatment of Triple Negative Breast Cancer".

Correction to "Discovery of Hydroxamic Acid Ester Derivatives as Second-Generation PRMT5 Inhibitors for the Treatment of Triple Negative Breast Cancer".

Journal: Journal of medicinal chemistry

Published: March 07, 2026

Discovery of Novel and Potent Dual PARP1/ERK Inhibitors as a Promising Strategy for Cancer Therapy.

Discovery of Novel and Potent Dual PARP1/ERK Inhibitors as a Promising Strategy for Cancer Therapy.

Journal: Journal of medicinal chemistry

Published: February 25, 2026

Discovery of Oxime Ether Derivatives as Second-Generation PRMT5 Inhibitors for the Treatment of Triple Negative Breast Cancer.

Discovery of Oxime Ether Derivatives as Second-Generation PRMT5 Inhibitors for the Treatment of Triple Negative Breast Cancer.

Journal: Journal of medicinal chemistry

Published: January 13, 2026

Discovery of PKMYT1 Inhibitors with a Novel Scaffold for the Treatment of Triple-Negative Breast Cancer.

Discovery of PKMYT1 Inhibitors with a Novel Scaffold for the Treatment of Triple-Negative Breast Cancer.

Journal: Journal of medicinal chemistry

Published: December 22, 2025

Discovery of Novel and Highly Potent Wee1 and HDAC Dual-Target Inhibitors for the Treatment of Acute Myeloid Leukemia.

Discovery of Novel and Highly Potent Wee1 and HDAC Dual-Target Inhibitors for the Treatment of Acute Myeloid Leukemia.

Journal: Journal of medicinal chemistry

Published: October 28, 2025

PARP7: an Emerging Therapeutic Target-Insights into Biological Functions and Advances in Small-Molecule Inhibitor Development.

PARP7: an Emerging Therapeutic Target-Insights into Biological Functions and Advances in Small-Molecule Inhibitor Development.

Journal: Journal of medicinal chemistry

Published: September 25, 2025

Discovery of Orally Potent Small-Molecule CD73 Inhibitor for Cancer Immunotherapy.

Discovery of Orally Potent Small-Molecule CD73 Inhibitor for Cancer Immunotherapy.

Journal: Journal of medicinal chemistry

Published: May 23, 2025

Discovery of highly potent PARP7 inhibitors for cancer immunotherapy.

Discovery of highly potent PARP7 inhibitors for cancer immunotherapy.

Journal: Bioorganic chemistry

Published: February 15, 2024

Discovery of Highly Potent Small-Molecule PD-1/PD-L1 Inhibitors with a Novel Scaffold for Cancer Immunotherapy.

Discovery of Highly Potent Small-Molecule PD-1/PD-L1 Inhibitors with a Novel Scaffold for Cancer Immunotherapy.

Journal: Journal of medicinal chemistry

Published: February 13, 2024

Discovery of Highly Selective PARP7 Inhibitors with a Novel Scaffold for Cancer Immunotherapy.

Discovery of Highly Selective PARP7 Inhibitors with a Novel Scaffold for Cancer Immunotherapy.

Journal: Journal of medicinal chemistry

Published: December 07, 2023

Advanced strategies in high-throughput droplet screening for enzyme engineering.

Advanced strategies in high-throughput droplet screening for enzyme engineering.

Journal: Biosensors & bioelectronics

Published: August 21, 2023

Showing 1-12 of 15

Last Updated: 09/26/2026