Wenyi Mei

Shanghai, 200062, China

Last Updated: 09/26/2026

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Found 17 publications

Pygenic Acid A, a Small-Molecule PD-1/SHP-2 Inhibitor, Enhances Efficacy of Therapeutic Melanoma Vaccines and Prophylactic Influenza Vaccines.

Pygenic Acid A, a Small-Molecule PD-1/SHP-2 Inhibitor, Enhances Efficacy of Therapeutic Melanoma Vaccines and Prophylactic Influenza Vaccines.

Journal: Virologica Sinica

Published: June 03, 2026

Discovery of 1,2-Diol TRPV4 Antagonists with Efficacy in a 3D Myocardial Fibrosis Organoid Model and a Murine TAC Pressure-Overload Model.

Discovery of 1,2-Diol TRPV4 Antagonists with Efficacy in a 3D Myocardial Fibrosis Organoid Model and a Murine TAC Pressure-Overload Model.

Journal: Journal of medicinal chemistry

Published: May 14, 2026

Direct Ser797 Interacted Pteridine-7(8H)-one Derivatives as Highly Selective and Orally Available EGFRL858R/T790M/C797S Inhibitors.

Direct Ser797 Interacted Pteridine-7(8H)-one Derivatives as Highly Selective and Orally Available EGFRL858R/T790M/C797S Inhibitors.

Journal: Journal of medicinal chemistry

Published: August 28, 2025

Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α1-Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents.

Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α1-Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents.

Journal: Journal of medicinal chemistry

Published: August 12, 2025

Exploring the macrocyclic chemical space for heuristic drug design with deep learning models.

Exploring the macrocyclic chemical space for heuristic drug design with deep learning models.

Journal: Communications chemistry

Published: July 14, 2025

Design, Synthesis, and Biological Evaluation of Macrocyclic 2-Amino-4-phenylaminopyrimidine Derivatives as Potent JAK2 Inhibitors.

Design, Synthesis, and Biological Evaluation of Macrocyclic 2-Amino-4-phenylaminopyrimidine Derivatives as Potent JAK2 Inhibitors.

Journal: Journal of medicinal chemistry

Published: June 26, 2025

Discovery of a Proteolysis-Targeting Chimera Degrader of JAK2 as a Potential Therapeutic Agent for JAK2-Mediated Myeloproliferative Neoplasms.

Discovery of a Proteolysis-Targeting Chimera Degrader of JAK2 as a Potential Therapeutic Agent for JAK2-Mediated Myeloproliferative Neoplasms.

Journal: Journal of medicinal chemistry

Published: June 03, 2025

Design, Synthesis, and Biological Evaluation of Pyrrolo[1,2-a]quinoxalin-4(5H)-one Derivatives as Potent and Orally Available Noncovalent Bruton's Tyrosine Kinase (BTK) Inhibitors.

Design, Synthesis, and Biological Evaluation of Pyrrolo[1,2-a]quinoxalin-4(5H)-one Derivatives as Potent and Orally Available Noncovalent Bruton's Tyrosine Kinase (BTK) Inhibitors.

Journal: Journal of medicinal chemistry

Published: April 07, 2025

Structure-based design of novel pyrrolo[1,2-a]quinoxalin-4(5H)-one derivatives as potent noncovalent Bruton's tyrosine kinase (BTK) inhibitors.

Structure-based design of novel pyrrolo[1,2-a]quinoxalin-4(5H)-one derivatives as potent noncovalent Bruton's tyrosine kinase (BTK) inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: March 17, 2025

Dentofacial deformities as independent predictors of sleep disorders: a cross-sectional study of young adults.

Dentofacial deformities as independent predictors of sleep disorders: a cross-sectional study of young adults.

Journal: BMC oral health

Published: November 09, 2024

Correction to "Discovery of Novel Non-Nucleoside Inhibitors Interacting with Dizinc Ions of CD73".

Correction to "Discovery of Novel Non-Nucleoside Inhibitors Interacting with Dizinc Ions of CD73".

Journal: Journal of medicinal chemistry

Published: September 30, 2024

Design, synthesis, and biological evaluation of diphenyl ether substituted quinazolin-4-amine derivatives as potent EGFRL858R/T790M/C797S inhibitors.

Design, synthesis, and biological evaluation of diphenyl ether substituted quinazolin-4-amine derivatives as potent EGFRL858R/T790M/C797S inhibitors.

Journal: European journal of medicinal chemistry

Published: July 17, 2024

Showing 1-12 of 17

Last Updated: 09/26/2026