Wesley P. Blackaby
Saffron Walden, ENG CB101XL, United Kingdom
Last Updated: 09/26/2026
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Found 9 publications
Discovery, Multiparametric Optimization, and Solid-State Driven Identification of CHF-6550, a Novel Soft Dual Pharmacology Muscarinic Antagonist and β2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases.
Journal: Journal of medicinal chemistry
Published: June 10, 2024
Optimization of M3 Antagonist-PDE4 Inhibitor (MAPI) Dual Pharmacology Molecules for the Treatment of COPD.
Journal: Journal of medicinal chemistry
Published: August 10, 2023
Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity.
Journal: Cancer discovery
Published: January 03, 2023
Discovery of Clinical Candidate CHF-6366: A Novel Super-soft Dual Pharmacology Muscarinic Antagonist and β2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases.
Journal: Journal of medicinal chemistry
Published: July 28, 2022
Discovery of M3 Antagonist-PDE4 Inhibitor Dual Pharmacology Molecules for the Treatment of Chronic Obstructive Pulmonary Disease.
Journal: Journal of medicinal chemistry
Published: June 18, 2021
Targeting the m6A RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication.
Journal: Genes & development
Published: January 25, 2021
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.
Journal: Nature
Published: December 18, 2020
Discovery of a novel class of inhaled dual pharmacology muscarinic antagonist and β2 agonist (MABA) for the treatment of chronic obstructive pulmonary disease (COPD).
Journal: Bioorganic & medicinal chemistry letters
Published: November 25, 2020
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Last Updated: 09/26/2026