Wilhelm J. Schwaeble

Cambridge, ENG CB30ES, United Kingdom

Last Updated: 09/26/2026

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Found 47 publications

Engineered antibodies bypass bacterial immune evasion to drive complement-mediated protection against lethal infections.

Engineered antibodies bypass bacterial immune evasion to drive complement-mediated protection against lethal infections.

Journal: Science translational medicine

Published: June 17, 2026

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID.

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID.

Journal: Immunology

Published: April 22, 2025

Inhibition of mannan-binding lectin associated serine protease (MASP)-2 reduces the cognitive deficits in a mouse model of severe traumatic brain injury.

Inhibition of mannan-binding lectin associated serine protease (MASP)-2 reduces the cognitive deficits in a mouse model of severe traumatic brain injury.

Journal: Journal of neuroinflammation

Published: March 30, 2024

Inhibition of the Lectin Pathway of Complement Activation Reduces Acute Respiratory Distress Syndrome Severity in a Mouse Model of SARS-CoV-2 Infection.

Inhibition of the Lectin Pathway of Complement Activation Reduces Acute Respiratory Distress Syndrome Severity in a Mouse Model of SARS-CoV-2 Infection.

Journal: The Journal of infectious diseases

Published: August 07, 2023

Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice.

Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice.

Journal: Frontiers in immunology

Published: March 23, 2023

Inhibition of the lectin pathway of complement ameliorates hypocomplementemia and restores serum bactericidal activity in patients with severe COVID-19.

Inhibition of the lectin pathway of complement ameliorates hypocomplementemia and restores serum bactericidal activity in patients with severe COVID-19.

Journal: Clinical and translational medicine

Published: May 22, 2022

Secondary Complement Deficiency Impairs Anti-Microbial Immunity to Klebsiella pneumoniae and Staphylococcus aureus During Severe Acute COVID-19.

Secondary Complement Deficiency Impairs Anti-Microbial Immunity to Klebsiella pneumoniae and Staphylococcus aureus During Severe Acute COVID-19.

Journal: Frontiers in immunology

Published: December 22, 2021

The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases?

The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases?

Journal: Journal of clinical medicine

Published: September 17, 2021

Analysis of Serological Biomarkers of SARS-CoV-2 Infection in Convalescent Samples From Severe, Moderate and Mild COVID-19 Cases.

Analysis of Serological Biomarkers of SARS-CoV-2 Infection in Convalescent Samples From Severe, Moderate and Mild COVID-19 Cases.

Journal: Frontiers in immunology

Published: July 27, 2021

Role of the lectin pathway of complement in hematopoietic stem cell transplantation-associated endothelial injury and thrombotic microangiopathy.

Role of the lectin pathway of complement in hematopoietic stem cell transplantation-associated endothelial injury and thrombotic microangiopathy.

Journal: Experimental hematology & oncology

Published: July 15, 2021

Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins.

Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins.

Journal: Frontiers in immunology

Published: May 25, 2021

Targeted deletions of complement lectin pathway genes improve outcome in traumatic brain injury, with MASP-2 playing a major role.

Targeted deletions of complement lectin pathway genes improve outcome in traumatic brain injury, with MASP-2 playing a major role.

Journal: Acta neuropathologica communications

Published: July 22, 2020

Showing 1-12 of 47

Last Updated: 09/26/2026