Willem K. Smits

Utrecht, UT, Netherlands

Last Updated: 09/26/2026

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Found 13 publications

Epithelial SLPI expression in severe inflammatory bowel disease relates to high IL-17 and neutrophil programming.

Epithelial SLPI expression in severe inflammatory bowel disease relates to high IL-17 and neutrophil programming.

Journal: JCI insight
Published: June 23, 2025

The role of the mineralocorticoid receptor in steroidinduced cytotoxicity in pediatric acute lymphoblastic leukemia.

The role of the mineralocorticoid receptor in steroidinduced cytotoxicity in pediatric acute lymphoblastic leukemia.

Journal: Haematologica
Published: February 10, 2023

Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia.

Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia.

Journal: Cell reports
Published: October 25, 2022

STAT5 does not drive steroid resistance in T-cell acute lymphoblastic leukemia despite the activation of BCL2 and BCLXL following glucocorticoid treatment.

STAT5 does not drive steroid resistance in T-cell acute lymphoblastic leukemia despite the activation of BCL2 and BCLXL following glucocorticoid treatment.

Journal: Haematologica
Published: November 23, 2021

MEF2C opposes Notch in lymphoid lineage decision and drives leukemia in the thymus.

MEF2C opposes Notch in lymphoid lineage decision and drives leukemia in the thymus.

Journal: JCI insight
Published: April 21, 2021

MAPK-ERK is a central pathway in T-cell acute lymphoblastic leukemia that drives steroid resistance.

MAPK-ERK is a central pathway in T-cell acute lymphoblastic leukemia that drives steroid resistance.

Journal: Leukemia
Published: October 28, 2020

Recurrent NR3C1 Aberrations at First Diagnosis Relate to Steroid Resistance in Pediatric T-Cell Acute Lymphoblastic Leukemia Patients.

Recurrent NR3C1 Aberrations at First Diagnosis Relate to Steroid Resistance in Pediatric T-Cell Acute Lymphoblastic Leukemia Patients.

Journal: HemaSphere
Published: July 01, 2020

Deletion 6q Drives T-cell Leukemia Progression by Ribosome Modulation.

Deletion 6q Drives T-cell Leukemia Progression by Ribosome Modulation.

Journal: Cancer discovery
Published: July 30, 2017

IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study.

IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study.

Journal: PLoS medicine
Published: August 03, 2016

Lentiviral gene transfer into human and murine hematopoietic stem cells: size matters.

Lentiviral gene transfer into human and murine hematopoietic stem cells: size matters.

Journal: BMC research notes
Published: February 19, 2016

PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events.

PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events.

Journal: Blood
Published: June 07, 2014

Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors.

Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors.

Journal: Haematologica
Published: August 27, 2013
Showing 1-12 of 13

Last Updated: 09/26/2026