Last Updated: 09/26/2026
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Found 102 publications
Stereology with OPEN-Stereo: low-cost, accessible, and accurate cellular quantification.
Journal: Scientific reports
Published: October 06, 2025
Preformed fibrils of α-synuclein rapidly activate LRRK2 on early endosomes, driving Rab5 phosphorylation and disrupting endolysosomal and synaptic function.
Journal: NPJ Parkinson's disease
Published: July 31, 2025
Tau pathology differs by sex in Alzheimer's disease in Down syndrome.
Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: June 27, 2025
Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease.
Journal: Genome research
Published: June 23, 2025
Harnessing the Neurobiology of Empathy and Compassion to Alleviate Burnout in Neurology.
Journal: Annals of neurology
Published: June 12, 2025
The history of Down syndrome-associated Alzheimer's disease; past, present, and future.
Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: January 26, 2025
Hyperactivation of RAB5 disrupts the endosomal Rab cascade leading to endolysosomal dysregulation in Down syndrome: A necessary role for increased APP gene dose.
Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: November 01, 2024
Antisense oligonucleotides directed against App and Rab5 normalized endosomal Rab activity and reversed DS-AD-linked degenerative phenotypes in the Dp16 mouse model of Down syndrome.
Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: October 31, 2024
Imagine, Discover, Inspire: Proceedings of the 4th International Conference of the Trisomy 21 Research Society.
Journal: Neuromolecular medicine
Published: October 07, 2024
Last Updated: 09/26/2026