William P. Sheffield

Hamilton, ON, Canada

Last Updated: 09/26/2026

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Found 87 publications

Corrigendum to "Substitution of reactive centre loop residues from C1 esterase inhibitor increases the inhibitory specificity of alpha-1 antitrypsin for plasma kallikrein" [J. Biotechnol. 405 (2025) 205-214].

Corrigendum to "Substitution of reactive centre loop residues from C1 esterase inhibitor increases the inhibitory specificity of alpha-1 antitrypsin for plasma kallikrein" [J. Biotechnol. 405 (2025) 205-214].

Journal: Journal of biotechnology

Published: November 09, 2025

Expression and purification of a broad-spectrum human protease inhibitor in Pichia pastoris.

Expression and purification of a broad-spectrum human protease inhibitor in Pichia pastoris.

Journal: Biochemistry and biophysics reports

Published: March 10, 2025

Substitution of reactive centre loop residues from C1 esterase inhibitor increases the inhibitory specificity of alpha-1 antitrypsin for plasma kallikrein.

Substitution of reactive centre loop residues from C1 esterase inhibitor increases the inhibitory specificity of alpha-1 antitrypsin for plasma kallikrein.

Journal: Journal of biotechnology

Published: February 04, 2025

Enhancement of plasma kallikrein specificity of antitrypsin variants identified by phage display and partial reversion.

Enhancement of plasma kallikrein specificity of antitrypsin variants identified by phage display and partial reversion.

Journal: BMC biotechnology

Published: October 07, 2024

Extension of the circulatory half-life of recombinant ecallantide via albumin fusion without loss of anti-kallikrein activity.

Extension of the circulatory half-life of recombinant ecallantide via albumin fusion without loss of anti-kallikrein activity.

Journal: Journal of biotechnology

Published: March 18, 2024

Prolonging the circulatory half-life of C1 esterase inhibitor via albumin fusion.

Prolonging the circulatory half-life of C1 esterase inhibitor via albumin fusion.

Journal: PloS one

Published: March 14, 2024

Human Fc gamma receptor IIIA blockade inhibits platelet destruction in a humanized murine model of ITP.

Human Fc gamma receptor IIIA blockade inhibits platelet destruction in a humanized murine model of ITP.

Journal: Blood advances

Published: November 13, 2023

Prehospital Freeze-Dried Plasma in Trauma: A Critical Review.

Prehospital Freeze-Dried Plasma in Trauma: A Critical Review.

Journal: Transfusion medicine reviews

Published: September 20, 2023

The under-appreciated world of the serpin family of serine proteinase inhibitors.

The under-appreciated world of the serpin family of serine proteinase inhibitors.

Journal: EMBO molecular medicine

Published: January 30, 2023

Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice.

Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice.

Journal: Scientific reports

Published: September 08, 2022

A positive blood culture is associated with a lower haemoglobin increment in hospitalized patients after red blood cell transfusion.

A positive blood culture is associated with a lower haemoglobin increment in hospitalized patients after red blood cell transfusion.

Journal: Vox sanguinis

Published: June 10, 2022

Spotlight on animal models of acute traumatic coagulopathy: an update.

Spotlight on animal models of acute traumatic coagulopathy: an update.

Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis

Published: March 14, 2022

Showing 1-12 of 87

Last Updated: 09/26/2026