Last Updated: 09/26/2026
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Found 109 publications
Context-dependent synthetic lethality - an emerging precision therapeutic approach.
Journal: Nature reviews. Cancer
Published: March 18, 2026
Mechanisms of clinical resistance to selective FGFR2 inhibition by lirafugratinib.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology
Published: July 27, 2025
Systematic cysteine scanning identifies a druggable pocket in oncogenic KRAS.
Journal: Cell chemical biology
Published: April 03, 2025
Targeting KIT With Antibody-Drug Conjugates in Chromophobe Renal Cell Carcinoma.
Journal: Clinical genitourinary cancer
Published: April 01, 2025
RAS Mutation-Specific Responses to Paralog- and State-Selective RAS Inhibitors.
Journal: Molecular cancer research : MCR
Published: March 31, 2025
Prospects for understanding and exploiting the consequences of hyperactivation lethality.
Journal: Trends in cancer
Published: February 26, 2025
Substrate adaptors are flexible tethering modules that enhance substrate methylation by the arginine methyltransferase PRMT5.
Journal: The Journal of biological chemistry
Published: November 01, 2024
A Kinetic Scout Approach Accelerates Targeted Protein Degrader Development.
Journal: bioRxiv : the preprint server for biology
Published: September 30, 2024
Identification of potent biparatopic antibodies targeting FGFR2 fusion driven cholangiocarcinoma.
Journal: bioRxiv : the preprint server for biology
Published: September 30, 2024
Generation of a Biliary Tract Cancer Cell Line Atlas Identifies Molecular Subtypes and Therapeutic Targets.
Journal: Cancer discovery
Published: September 26, 2024
Last Updated: 09/26/2026