Wim M. De Lau
Utrecht, UT 3584CX, Netherlands
Last Updated: 09/26/2026
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Found 14 publications
Controlling Intestinal Organoid Polarity using Synthetic Dynamic Hydrogels Decorated with Laminin-Derived IKVAV Peptides.
Journal: Advanced healthcare materials
Published: April 24, 2025
Integrin-activating Yersinia protein Invasin sustains long-term expansion of primary epithelial cells as 2D organoid sheets.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: January 10, 2025
A single-chain derivative of an integrin-activating antibody potentiates organoid growth in Matrigel and collagen hydrogels.
Journal: Nature biotechnology
Published: May 24, 2023
A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses.
Journal: Nature communications
Published: July 01, 2021
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo.
Journal: Cell stem cell
Published: December 19, 2019
Syndecan-1 promotes Wnt/β-catenin signaling in multiple myeloma by presenting Wnts and R-spondins.
Journal: Blood
Published: July 19, 2017
Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: December 29, 2016
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling.
Journal: Nature
Published: May 03, 2016
The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength.
Journal: Genes & development
Published: February 18, 2014
Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling.
Journal: PloS one
Published: October 11, 2013
Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells.
Journal: Stem cells (Dayton, Ohio)
Published: September 13, 2012
Last Updated: 09/26/2026