Wojciech Kopec

Goettingen, NI, Germany

Last Updated: 09/26/2026

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Found 37 publications

Hydrophobic and lipid-mediated gating mechanism revealed by low-conductance MthK mutants.

Hydrophobic and lipid-mediated gating mechanism revealed by low-conductance MthK mutants.

Journal: bioRxiv : the preprint server for biology

Published: May 07, 2026

Deep learning as a generator of sodium channel state hypotheses.

Deep learning as a generator of sodium channel state hypotheses.

Journal: The Journal of general physiology

Published: March 10, 2026

One pocket to activate them all (?): Efforts on understanding the modulator pocket in K2P channels.

One pocket to activate them all (?): Efforts on understanding the modulator pocket in K2P channels.

Journal: Channels (Austin, Tex.)

Published: December 23, 2025

Light-induced analgesia provides a drug-free optical method for pain relief via activation of TRAAK k+ channels.

Light-induced analgesia provides a drug-free optical method for pain relief via activation of TRAAK k+ channels.

Journal: Nature communications

Published: June 24, 2025

Asymmetric Nature of MscL Opening Revealed by Molecular Dynamics Simulations.

Asymmetric Nature of MscL Opening Revealed by Molecular Dynamics Simulations.

Journal: Journal of chemical information and modeling

Published: June 05, 2025

Effective polarization in potassium channel simulations: Ion conductance, occupancy, voltage response, and selectivity.

Effective polarization in potassium channel simulations: Ion conductance, occupancy, voltage response, and selectivity.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: May 20, 2025

Cryo-EM structure of the human THIK-1 K2P K+ channel reveals a lower Y gate regulated by lipids and anesthetics.

Cryo-EM structure of the human THIK-1 K2P K+ channel reveals a lower Y gate regulated by lipids and anesthetics.

Journal: Nature structural & molecular biology

Published: July 19, 2024

Selectivity filter mutations shift ion permeation mechanism in potassium channels.

Selectivity filter mutations shift ion permeation mechanism in potassium channels.

Journal: PNAS nexus

Published: April 29, 2024

Effect of two activators on the gating of a K2P channel.

Effect of two activators on the gating of a K2P channel.

Journal: Biophysical journal

Published: April 22, 2024

Biomolecular simulations at the exascale: From drug design to organelles and beyond.

Biomolecular simulations at the exascale: From drug design to organelles and beyond.

Journal: Current opinion in structural biology

Published: December 24, 2023

Interactions between selectivity filter and pore helix control filter gating in the MthK channel.

Interactions between selectivity filter and pore helix control filter gating in the MthK channel.

Journal: The Journal of general physiology

Published: March 29, 2022

The Persistent Question of Potassium Channel Permeation Mechanisms.

The Persistent Question of Potassium Channel Permeation Mechanisms.

Journal: Journal of molecular biology

Published: February 05, 2021

Showing 1-12 of 37

Last Updated: 09/26/2026