Wolfgang Haap

Basel, BS 4070, Switzerland

Last Updated: 09/26/2026

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Found 26 publications

Modular assembly and property profiling of an expansive, shape-defined library of pentacyclic saturated N-heterocycles.

Modular assembly and property profiling of an expansive, shape-defined library of pentacyclic saturated N-heterocycles.

Journal: Chemical science
Published: July 03, 2026

Selectride-Mediated Cleavage of 3-Picolyl and 3-Picolyloxycarbonyl Groups.

Selectride-Mediated Cleavage of 3-Picolyl and 3-Picolyloxycarbonyl Groups.

Journal: Organic letters
Published: June 26, 2026

Machine Learning-Assisted Iterative Screening for Efficient Detection of Drug Discovery Starting Points.

Machine Learning-Assisted Iterative Screening for Efficient Detection of Drug Discovery Starting Points.

Journal: Journal of medicinal chemistry
Published: July 14, 2025

Discovery of a Potent SARM1 Base-Exchange Inhibitor with In Vivo Efficacy.

Discovery of a Potent SARM1 Base-Exchange Inhibitor with In Vivo Efficacy.

Journal: Journal of medicinal chemistry
Published: March 18, 2025

Inhibition of Cathepsin S in Autoimmune CD25KO Mouse Improves Sjögren Disease-Like Lacrimal Gland Pathology.

Inhibition of Cathepsin S in Autoimmune CD25KO Mouse Improves Sjögren Disease-Like Lacrimal Gland Pathology.

Journal: Investigative ophthalmology & visual science
Published: July 17, 2024

Effects of Cathepsin S Inhibition in the Age-Related Dry Eye Phenotype.

Effects of Cathepsin S Inhibition in the Age-Related Dry Eye Phenotype.

Journal: Investigative ophthalmology & visual science
Published: August 04, 2023

Peptide barcodes meet drug discovery.

Peptide barcodes meet drug discovery.

Journal: Science (New York, N.Y.)
Published: March 02, 2023

Drug Discovery Efforts to Identify Novel Treatments for Neglected Tropical Diseases - Cysteine Protease Inhibitors.

Drug Discovery Efforts to Identify Novel Treatments for Neglected Tropical Diseases - Cysteine Protease Inhibitors.

Journal: Current medicinal chemistry
Published: February 14, 2023

Small-Molecule Lead-Finding Trends across the Roche and Genentech Research Organizations.

Small-Molecule Lead-Finding Trends across the Roche and Genentech Research Organizations.

Journal: Journal of medicinal chemistry
Published: February 09, 2022

What We Learned in 25 Years of Interactive Molecular Design Sessions.

What We Learned in 25 Years of Interactive Molecular Design Sessions.

Journal: ChemMedChem
Published: May 20, 2021

DOTAM-Based, Targeted, Activatable Fluorescent Probes for the Highly Sensitive and Selective Detection of Cancer Cells.

DOTAM-Based, Targeted, Activatable Fluorescent Probes for the Highly Sensitive and Selective Detection of Cancer Cells.

Journal: Bioconjugate chemistry
Published: March 10, 2021

2 H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design.

2 H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design.

Journal: Journal of medicinal chemistry
Published: March 30, 2018
Showing 1-12 of 26

Last Updated: 09/26/2026