Won-sik S. Shim

Incheon, Republic of Korea

Last Updated: 09/26/2026

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Found 54 publications

TRPV4 Activation Promotes Hair Growth via TSLP Signaling in the Skin.

TRPV4 Activation Promotes Hair Growth via TSLP Signaling in the Skin.

Journal: Biomolecules & therapeutics

Published: April 06, 2026

Synthetic Strategy and Evaluation of the Benzyloxy Benzylamide Derivatives as Thymic Stromal Lymphopoietin Modulators for the Treatment of Atopic Dermatitis.

Synthetic Strategy and Evaluation of the Benzyloxy Benzylamide Derivatives as Thymic Stromal Lymphopoietin Modulators for the Treatment of Atopic Dermatitis.

Journal: Journal of medicinal chemistry

Published: December 30, 2025

Azelaic acid potentiates TRPV3 activity as a mechanism for skin irritation.

Azelaic acid potentiates TRPV3 activity as a mechanism for skin irritation.

Journal: The Journal of investigative dermatology

Published: September 02, 2025

Blockade of PAR2 Signaling by Punicalagin as a Therapeutic Strategy for Atopic Dermatitis.

Blockade of PAR2 Signaling by Punicalagin as a Therapeutic Strategy for Atopic Dermatitis.

Journal: International journal of molecular sciences

Published: August 15, 2025

Vitexin alleviates atopic dermatitis-associated itch via TRPV4 inhibition in sensory neurons and MRGPRX2/MrgprB2 blockade in mast cells.

Vitexin alleviates atopic dermatitis-associated itch via TRPV4 inhibition in sensory neurons and MRGPRX2/MrgprB2 blockade in mast cells.

Journal: International immunopharmacology

Published: July 22, 2025

OPRM1/MRGPRX1 heterodimers drive opioid-induced itch through a peripheral mechanism.

OPRM1/MRGPRX1 heterodimers drive opioid-induced itch through a peripheral mechanism.

Journal: Journal of biomedical science

Published: July 02, 2025

Sphingosylphosphorylcholine induces itch via activation of TRPM3 and TRPA1 in mice.

Sphingosylphosphorylcholine induces itch via activation of TRPM3 and TRPA1 in mice.

Journal: Biochemical pharmacology

Published: October 23, 2024

Identification of KMH-45, a novel MRGPRX2 inhibitor with enhanced anti-pruritic properties.

Identification of KMH-45, a novel MRGPRX2 inhibitor with enhanced anti-pruritic properties.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: September 26, 2024

Antipruritic effect of ursolic acid through MRGPRX2/MrgprB2-dependent inhibition of mast cell degranulation and reduced TSLP production.

Antipruritic effect of ursolic acid through MRGPRX2/MrgprB2-dependent inhibition of mast cell degranulation and reduced TSLP production.

Journal: European journal of pharmacology

Published: May 04, 2024

Anoctamin 1, a multi-modal player in pain and itch.

Anoctamin 1, a multi-modal player in pain and itch.

Journal: Cell calcium

Published: March 04, 2024

A phytosphingosine derivative mYG-II-6 inhibits histamine-mediated TRPV1 activation and MRGPRX2-dependent mast cell degranulation.

A phytosphingosine derivative mYG-II-6 inhibits histamine-mediated TRPV1 activation and MRGPRX2-dependent mast cell degranulation.

Journal: International immunopharmacology

Published: February 10, 2024

The transient receptor potential vanilloid-3 (TRPV3) channel in epidermal keratinocytes induce thymic interstitial lymphopoietin: Implications for TRPV3-mediated itch pathways.

The transient receptor potential vanilloid-3 (TRPV3) channel in epidermal keratinocytes induce thymic interstitial lymphopoietin: Implications for TRPV3-mediated itch pathways.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

Published: April 13, 2023

Showing 1-12 of 54

Last Updated: 09/26/2026