Wouter De Laat

Uppsalalaan 8, 3584, CT
Utrecht, UT, Netherlands

Last Updated: 09/26/2026

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Found 83 publications

Reactivation of developmentally silenced globin genes through forced linear recruitment of remote enhancers.

Reactivation of developmentally silenced globin genes through forced linear recruitment of remote enhancers.

Journal: Blood

Published: December 17, 2024

Long-range enhancer-controlled genes are hypersensitive to regulatory factor perturbations.

Long-range enhancer-controlled genes are hypersensitive to regulatory factor perturbations.

Journal: Cell genomics

Published: October 31, 2024

Characterization of induced cohesin loop extrusion trajectories in living cells.

Characterization of induced cohesin loop extrusion trajectories in living cells.

Journal: Nature genetics

Published: October 27, 2024

Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity.

Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity.

Journal: Nature communications

Published: September 27, 2024

Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain.

Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain.

Journal: Genes & development

Published: August 19, 2024

A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs.

A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs.

Journal: Cell genomics

Published: March 16, 2023

Formalin-Fixed, Paraffin-Embedded-Targeted Locus Capture: A Next-Generation Sequencing Technology for Accurate DNA-Based Gene Fusion Detection in Bone and Soft Tissue Tumors.

Formalin-Fixed, Paraffin-Embedded-Targeted Locus Capture: A Next-Generation Sequencing Technology for Accurate DNA-Based Gene Fusion Detection in Bone and Soft Tissue Tumors.

Journal: The Journal of molecular diagnostics : JMD

Published: February 28, 2023

Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia.

Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia.

Journal: Cell reports

Published: October 25, 2022

Current challenges in understanding the role of enhancers in disease.

Current challenges in understanding the role of enhancers in disease.

Journal: Nature structural & molecular biology

Published: September 30, 2022

CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands.

CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands.

Journal: Nucleic acids research

Published: August 09, 2022

Building regulatory landscapes reveals that an enhancer can recruit cohesin to create contact domains, engage CTCF sites and activate distant genes.

Building regulatory landscapes reveals that an enhancer can recruit cohesin to create contact domains, engage CTCF sites and activate distant genes.

Journal: Nature structural & molecular biology

Published: December 23, 2021

A public-private partnership model for COVID-19 diagnostics.

A public-private partnership model for COVID-19 diagnostics.

Journal: Nature biotechnology

Published: September 29, 2021

Showing 1-12 of 83

Last Updated: 09/26/2026