Wukun Q. Liu

Königin Luise Str 2+4
Berlin, BE 14195, Germany

Last Updated: 09/26/2026

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Found 63 publications

Drug-Conjugated Tam-NHC-Gold(I) Complexes Overcome ESR1 Mutant Breast Cancer Resistance and Downregulate the RAMP3/CALCR Signaling Pathway.

Drug-Conjugated Tam-NHC-Gold(I) Complexes Overcome ESR1 Mutant Breast Cancer Resistance and Downregulate the RAMP3/CALCR Signaling Pathway.

Journal: Journal of medicinal chemistry

Published: June 30, 2026

Gold(I)-Loaded Nanomedicine for Liver Cancer: A Closed-Loop Strategy Integrating Ferritinophagy-Driven Ferroptosis and Immunotherapy.

Gold(I)-Loaded Nanomedicine for Liver Cancer: A Closed-Loop Strategy Integrating Ferritinophagy-Driven Ferroptosis and Immunotherapy.

Journal: Journal of medicinal chemistry

Published: June 10, 2026

Inhibitors of Ectonucleotidase CD39 for Immunotherapy of Cancer and Infections─Recent Developments and Future Perspectives.

Inhibitors of Ectonucleotidase CD39 for Immunotherapy of Cancer and Infections─Recent Developments and Future Perspectives.

Journal: Journal of medicinal chemistry

Published: May 04, 2026

Novel Dual-Pharmacophore TrxR Inhibitors Integrating Ferroptosis and Antitumor Immunity: A Closed-Loop Strategy for TIME Remodeling.

Novel Dual-Pharmacophore TrxR Inhibitors Integrating Ferroptosis and Antitumor Immunity: A Closed-Loop Strategy for TIME Remodeling.

Journal: Journal of medicinal chemistry

Published: April 24, 2026

Au(III) Complexes as Pyroptosis Inducers by Targeting Mitochondrial DNA for Tumor Immunity.

Au(III) Complexes as Pyroptosis Inducers by Targeting Mitochondrial DNA for Tumor Immunity.

Journal: Angewandte Chemie (International ed. in English)

Published: December 21, 2025

Discovery and development of the preclinical candidate (SH-1092), a potent third generation EGFR inhibitor for the treatment of NSCLC.

Discovery and development of the preclinical candidate (SH-1092), a potent third generation EGFR inhibitor for the treatment of NSCLC.

Journal: Bioorganic chemistry

Published: November 07, 2025

Isoalantolactone induces AML pyroptosis and potentiates α-PD-1 efficacy by targeting selenoprotein TXNRD1.

Isoalantolactone induces AML pyroptosis and potentiates α-PD-1 efficacy by targeting selenoprotein TXNRD1.

Journal: Acta pharmaceutica Sinica. B

Published: August 03, 2025

Au(III) Schiff base complexes as oxidoreductase inhibitors against carbapenem- and colistin-resistant Gram-negative bacteria via targeting redox active motifs.

Au(III) Schiff base complexes as oxidoreductase inhibitors against carbapenem- and colistin-resistant Gram-negative bacteria via targeting redox active motifs.

Journal: Redox biology

Published: July 01, 2025

Application of master protocol design in the clinical evaluation of infectious disease vaccines

Application of master protocol design in the clinical evaluation of infectious disease vaccines

Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

Published: April 24, 2025

Glabridin-Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity.

Glabridin-Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: March 14, 2025

Evaluating indole‑gold(I) based complexes as potential anti lymphoma agents by disrupting the thioredoxin reductase/glutathione peroxidase axis.

Evaluating indole‑gold(I) based complexes as potential anti lymphoma agents by disrupting the thioredoxin reductase/glutathione peroxidase axis.

Journal: Journal of inorganic biochemistry

Published: March 13, 2025

Dual-Targeting TrxR-EGFR Alkynyl-Au(I) Gefitinib Complex Induces Ferroptosis in Gefitinib-Resistant Lung Cancer via Degradation of GPX4.

Dual-Targeting TrxR-EGFR Alkynyl-Au(I) Gefitinib Complex Induces Ferroptosis in Gefitinib-Resistant Lung Cancer via Degradation of GPX4.

Journal: Journal of medicinal chemistry

Published: February 19, 2025

Showing 1-12 of 63

Last Updated: 09/26/2026