Wynand P. Roos

Obere Zahlbacher Str. 67
Mainz, RP 55131, Germany

Last Updated: 09/26/2026

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Found 39 publications

Corrigendum to "Oleandrin-mediated suppression of MELK induces apoptosis, autophagy, and ferroptosis in human non-small cell lung cancer cells" [Phytomedicine. 2025 Nov;147:157173].

Corrigendum to "Oleandrin-mediated suppression of MELK induces apoptosis, autophagy, and ferroptosis in human non-small cell lung cancer cells" [Phytomedicine. 2025 Nov;147:157173].

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: August 15, 2026

Visualization and Quantitative Analysis of Genotoxin-induced PARP1/PARP2 Activation in Cells using a Fluorescent Fusion Protein-based Reporter.

Visualization and Quantitative Analysis of Genotoxin-induced PARP1/PARP2 Activation in Cells using a Fluorescent Fusion Protein-based Reporter.

Journal: Journal of visualized experiments : JoVE

Published: May 04, 2026

Hypomorphic Protein Expression of DNA Polymerase Beta in PolβL301R-V303R/L301R-V303R Knock-In Transgenic Mice Does Not Impact Global DNA Methylation Levels in the Midbrain.

Hypomorphic Protein Expression of DNA Polymerase Beta in PolβL301R-V303R/L301R-V303R Knock-In Transgenic Mice Does Not Impact Global DNA Methylation Levels in the Midbrain.

Journal: Biomolecules

Published: January 19, 2026

Synergistic Cellular Toxicity from Inhibition of Poly(ADP-ribose) Glycohydrolase (PARG) and Ubiquitin-Specific Protease 1 (USP1).

Synergistic Cellular Toxicity from Inhibition of Poly(ADP-ribose) Glycohydrolase (PARG) and Ubiquitin-Specific Protease 1 (USP1).

Journal: Toxics

Published: January 13, 2026

Ubiquitylation of DNA polymerase β via atypical K27 chains signals a DNA damage response.

Ubiquitylation of DNA polymerase β via atypical K27 chains signals a DNA damage response.

Journal: Nucleic acids research

Published: December 12, 2025

AAV Kills Dividing Cells by Depleting PARP1 and Other DNA Damage Response Proteins.

AAV Kills Dividing Cells by Depleting PARP1 and Other DNA Damage Response Proteins.

Journal: bioRxiv : the preprint server for biology

Published: November 24, 2025

Replication-associated base excision repair/single-strand break repair regulates PARG inhibitor response via the PRMT1/PRMT5/ATR axis.

Replication-associated base excision repair/single-strand break repair regulates PARG inhibitor response via the PRMT1/PRMT5/ATR axis.

Journal: NAR cancer

Published: August 19, 2025

DNA polymerase beta expression in head & neck cancer modulates the poly(ADP-ribose)-mediated replication checkpoint.

DNA polymerase beta expression in head & neck cancer modulates the poly(ADP-ribose)-mediated replication checkpoint.

Journal: DNA repair

Published: January 20, 2025

Oleandrin-mediated suppression of MELK induces apoptosis, autophagy, and ferroptosis in human non-small cell lung cancer cells.

Oleandrin-mediated suppression of MELK induces apoptosis, autophagy, and ferroptosis in human non-small cell lung cancer cells.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: November 08, 2024

TRIP12's role in the governance of DNA polymerase β involvement in DNA damage response and repair.

TRIP12's role in the governance of DNA polymerase β involvement in DNA damage response and repair.

Journal: Nucleic acids research

Published: April 12, 2024

Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage.

Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage.

Journal: DNA repair

Published: January 04, 2024

Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity.

Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity.

Journal: DNA repair

Published: March 10, 2023

Showing 1-12 of 39

Last Updated: 09/26/2026