Xavier Momblona-Hernando
Barcelona, CT, Spain
Last Updated: 09/26/2026
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Found 17 publications
A Plastic EMP1+ to LGR5+ Cell State Conversion as a Bypass to KRASG12D Pharmacologic Inhibition in Metastatic Colorectal Cancer.
Journal: Cancer discovery
Published: April 23, 2025
TGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages.
Journal: Nature genetics
Published: August 16, 2024
New Potent Inhibitor of Transforming Growth Factor-Beta (TGFβ) Signaling that is Efficacious against Microsatellite Stable Colorectal Cancer Metastasis in Combination with Immune Checkpoint Therapy in Mice.
Journal: ACS pharmacology & translational science
Published: June 20, 2024
FixNCut: single-cell genomics through reversible tissue fixation and dissociation.
Journal: Genome biology
Published: April 12, 2023
Modeling Biochemical Gradients In Vitro to Control Cell Compartmentalization in a Microengineered 3D Model of the Intestinal Epithelium.
Journal: Advanced healthcare materials
Published: June 16, 2022
Long-term platinum-based drug accumulation in cancer-associated fibroblasts promotes colorectal cancer progression and resistance to therapy.
Journal: Nature communications
Published: January 25, 2022
Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells.
Journal: Nature
Published: December 13, 2021
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors.
Journal: Nature cancer
Published: August 10, 2020
Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer.
Journal: Cell stem cell
Published: July 04, 2019
A genome editing approach to study cancer stem cells in human tumors.
Journal: EMBO molecular medicine
Published: May 05, 2017
Last Updated: 09/26/2026