Xi Zhou

Changsha, 410081, China

Last Updated: 09/26/2026

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Found 36 publications

Discovery of 1H-Indole-3-Propionamide Derivatives as Potent, Selective and Orally Available NaV1.7 Inhibitors for Pain Treatment.

Discovery of 1H-Indole-3-Propionamide Derivatives as Potent, Selective and Orally Available NaV1.7 Inhibitors for Pain Treatment.

Journal: Journal of medicinal chemistry

Published: July 27, 2026

BioTD: An Online Database of Biotoxins.

BioTD: An Online Database of Biotoxins.

Journal: Journal of chemical information and modeling

Published: June 02, 2026

Structural basis for inhibition of the voltage-gated sodium channel NaV1.7 by the tarantula toxin HWTX-I.

Structural basis for inhibition of the voltage-gated sodium channel NaV1.7 by the tarantula toxin HWTX-I.

Journal: The Journal of biological chemistry

Published: November 07, 2025

Discovery of a novel Nav1.5 inhibitor reducing cardiac conduction via structure-based virtual screening and assays.

Discovery of a novel Nav1.5 inhibitor reducing cardiac conduction via structure-based virtual screening and assays.

Journal: Acta pharmacologica Sinica

Published: May 28, 2025

Isolation and identification of toxins inhibiting Shal potassium channels from the venom of Ornithoctonus hainana spider.

Isolation and identification of toxins inhibiting Shal potassium channels from the venom of Ornithoctonus hainana spider.

Journal: Toxicology and applied pharmacology

Published: February 07, 2025

A novel spider toxin as a selective antagonist of the Kv1 subfamily of voltage-gated potassium channels through gating modulation.

A novel spider toxin as a selective antagonist of the Kv1 subfamily of voltage-gated potassium channels through gating modulation.

Journal: The Journal of biological chemistry

Published: December 29, 2024

Discovery of Novel Nav1.7-Selective Inhibitors with the 1H-Indole-3-Propionamide Scaffold for Effective Pain Relief.

Discovery of Novel Nav1.7-Selective Inhibitors with the 1H-Indole-3-Propionamide Scaffold for Effective Pain Relief.

Journal: Research (Washington, D.C.)

Published: November 19, 2024

Inherent fast inactivation particle of Nav channels as a new binding site for a neurotoxin.

Inherent fast inactivation particle of Nav channels as a new binding site for a neurotoxin.

Journal: The EMBO journal

Published: September 30, 2024

CAP superfamily proteins in human: a new target for cancer therapy.

CAP superfamily proteins in human: a new target for cancer therapy.

Journal: Medical oncology (Northwood, London, England)

Published: September 11, 2024

Multiple gating processes associated with the distal end of the S6 segment of domain II in the Nav channels.

Multiple gating processes associated with the distal end of the S6 segment of domain II in the Nav channels.

Journal: The Journal of biological chemistry

Published: September 02, 2024

Elucidating the roles of voltage sensors in NaV1.9 activation and inactivation through a spider toxin.

Elucidating the roles of voltage sensors in NaV1.9 activation and inactivation through a spider toxin.

Journal: Biochimica et biophysica acta. General subjects

Published: August 23, 2024

Novel design of potent anti-tumour activity of IL-2 prodrug by FAPα-mediated activation.

Novel design of potent anti-tumour activity of IL-2 prodrug by FAPα-mediated activation.

Journal: International journal of biological macromolecules

Published: June 28, 2024

Showing 1-12 of 36

Last Updated: 09/26/2026