Xia Wu

State Key Laboratory Of Bioreactor Engineering
Shanghai, 200237, China

Last Updated: 09/26/2026

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Found 16 publications

Novel AAV843 Vector-Mediated Gene Replacement Therapy Rescues Primary Hyperoxaluria Type I in Mice.

Novel AAV843 Vector-Mediated Gene Replacement Therapy Rescues Primary Hyperoxaluria Type I in Mice.

Journal: Cells

Published: February 13, 2026

Factor IX-Padua AAV gene therapy in hemophilia B: phases 1/2 and 3 trials.

Factor IX-Padua AAV gene therapy in hemophilia B: phases 1/2 and 3 trials.

Journal: Nature medicine

Published: March 02, 2025

BDNF gene therapy rescues neuronal function via unique and common transcriptional responses in Aβ and tau-driven Alzheimer's disease mouse models.

BDNF gene therapy rescues neuronal function via unique and common transcriptional responses in Aβ and tau-driven Alzheimer's disease mouse models.

Journal: Biochemistry and biophysics reports

Published: February 28, 2025

Co-delivery of IL-1Ra and SOX9 via AAV inhibits inflammation and promotes cartilage repair in surgically induced osteoarthritis animal models.

Co-delivery of IL-1Ra and SOX9 via AAV inhibits inflammation and promotes cartilage repair in surgically induced osteoarthritis animal models.

Journal: Gene therapy

Published: October 29, 2024

Hippocampus-targeted BDNF gene therapy to rescue cognitive impairments of Alzheimer's disease in multiple mouse models.

Hippocampus-targeted BDNF gene therapy to rescue cognitive impairments of Alzheimer's disease in multiple mouse models.

Journal: Genes & diseases

Published: June 28, 2024

Activated factor X delivered by adeno-associated virus significantly inhibited bleeding and alleviated hemophilic synovitis in hemophilic mice.

Activated factor X delivered by adeno-associated virus significantly inhibited bleeding and alleviated hemophilic synovitis in hemophilic mice.

Journal: Gene therapy

Published: December 05, 2023

Engineering miniature CRISPR-Cas Un1Cas12f1 for efficient base editing.

Engineering miniature CRISPR-Cas Un1Cas12f1 for efficient base editing.

Journal: Molecular therapy. Nucleic acids

Published: October 04, 2023

Robust miniature Cas-based transcriptional modulation by engineering Un1Cas12f1 and tethering Sso7d.

Robust miniature Cas-based transcriptional modulation by engineering Un1Cas12f1 and tethering Sso7d.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: October 03, 2023

Prevention of Portal-Tract Fibrosis in Zfyve19-/- Mouse Model with Adeno-Associated Virus Vector Delivering ZFYVE19.

Prevention of Portal-Tract Fibrosis in Zfyve19-/- Mouse Model with Adeno-Associated Virus Vector Delivering ZFYVE19.

Journal: Human gene therapy

Published: September 06, 2023

Sildenafil increases AAV9 transduction after a systemic administration and enhances AAV9-dystrophin therapeutic effect in mdx mice.

Sildenafil increases AAV9 transduction after a systemic administration and enhances AAV9-dystrophin therapeutic effect in mdx mice.

Journal: Gene therapy

Published: December 20, 2022

Study on the Therapeutic Effect of Lenalidomide on Hemophilic Arthropathy

Study on the Therapeutic Effect of Lenalidomide on Hemophilic Arthropathy

Journal: Zhongguo shi yan xue ye xue za zhi

Published: October 08, 2022

Safety and activity of an engineered, liver-tropic adeno-associated virus vector expressing a hyperactive Padua factor IX administered with prophylactic glucocorticoids in patients with haemophilia B: a single-centre, single-arm, phase 1, pilot trial.

Safety and activity of an engineered, liver-tropic adeno-associated virus vector expressing a hyperactive Padua factor IX administered with prophylactic glucocorticoids in patients with haemophilia B: a single-centre, single-arm, phase 1, pilot trial.

Journal: The Lancet. Haematology

Published: February 23, 2022

Showing 1-12 of 16

Last Updated: 09/26/2026