Xianglei Zhang

393 Middle Huaxia Road
Shanghai, 201210, China

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 20 publications

Molecular Mechanism of Fungal Effector PevD1-NRP Interaction and Discovery of a Small-Molecule Disruptor.

Molecular Mechanism of Fungal Effector PevD1-NRP Interaction and Discovery of a Small-Molecule Disruptor.

Journal: The Journal of biological chemistry

Published: May 06, 2026

Exploring chemical space based on Transformation to design broad-spectrum 3CLpro inhibitors against coronavirus.

Exploring chemical space based on Transformation to design broad-spectrum 3CLpro inhibitors against coronavirus.

Journal: European journal of medicinal chemistry

Published: April 22, 2026

Dual inhibition of KDM4B and KDM5A disassembles the PAX3-FOXO1 transcriptional program in fusion-positive rhabdomyosarcoma.

Dual inhibition of KDM4B and KDM5A disassembles the PAX3-FOXO1 transcriptional program in fusion-positive rhabdomyosarcoma.

Journal: Biology direct

Published: April 02, 2026

DeepDegradome: A structure-aware deep learning framework for PROTAC and ligand generation against protein targets.

DeepDegradome: A structure-aware deep learning framework for PROTAC and ligand generation against protein targets.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: March 12, 2026

Design and biological evaluation of peptide disruptors targeting YAP1-TEAD interaction for oral cancer.

Design and biological evaluation of peptide disruptors targeting YAP1-TEAD interaction for oral cancer.

Journal: BMC oral health

Published: February 13, 2025

Motif-guided identification of KRAS-interacting proteins.

Motif-guided identification of KRAS-interacting proteins.

Journal: BMC biology

Published: May 28, 2024

Accurate Characterization of Binding Kinetics and Allosteric Mechanisms for the HSP90 Chaperone Inhibitors Using AI-Augmented Integrative Biophysical Studies.

Accurate Characterization of Binding Kinetics and Allosteric Mechanisms for the HSP90 Chaperone Inhibitors Using AI-Augmented Integrative Biophysical Studies.

Journal: JACS Au

Published: February 09, 2024

Computer-Aided Prediction of the Interactions of Viral Proteases with Antiviral Drugs: Antiviral Potential of Broad-Spectrum Drugs.

Computer-Aided Prediction of the Interactions of Viral Proteases with Antiviral Drugs: Antiviral Potential of Broad-Spectrum Drugs.

Journal: Molecules (Basel, Switzerland)

Published: November 29, 2023

Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors.

Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors.

Journal: European journal of medicinal chemistry

Published: September 10, 2023

Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group.

Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group.

Journal: Journal of medicinal chemistry

Published: August 18, 2023

Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1.

Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1.

Journal: Signal transduction and targeted therapy

Published: July 12, 2023

Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of RORγ antagonists.

Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of RORγ antagonists.

Journal: European journal of medicinal chemistry

Published: March 16, 2023

Showing 1-12 of 20

Last Updated: 09/26/2026