Xianglian Ge

State Key Laboratory And Key Laboratory Of Vision Science, Ministry Of Health And Zhejiang Provincial Key Laboratory Of Ophthalmology And Optometry
Wenzhou, China

Last Updated: 09/26/2026

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Found 15 publications

High-fidelity SaCas9 identified by directional screening in human cells.

High-fidelity SaCas9 identified by directional screening in human cells.

Journal: PLoS biology

Published: February 12, 2020

Engineering the Direct Repeat Sequence of crRNA for Optimization of FnCpf1-Mediated Genome Editing in Human Cells.

Engineering the Direct Repeat Sequence of crRNA for Optimization of FnCpf1-Mediated Genome Editing in Human Cells.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: March 10, 2018

A Single Multiplex crRNA Array for FnCpf1-Mediated Human Genome Editing.

A Single Multiplex crRNA Array for FnCpf1-Mediated Human Genome Editing.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: February 08, 2018

SaCas9 Requires 5'-NNGRRT-3' PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells.

SaCas9 Requires 5'-NNGRRT-3' PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells.

Journal: Biotechnology journal

Published: February 06, 2018

Functional non-homologous end joining patterns triggered by CRISPR/Cas9 in human cells.

Functional non-homologous end joining patterns triggered by CRISPR/Cas9 in human cells.

Journal: Journal of genetics and genomics = Yi chuan xue bao

Published: January 07, 2018

Recapitulating X-Linked Juvenile Retinoschisis in Mouse Model by Knock-In Patient-Specific Novel Mutation.

Recapitulating X-Linked Juvenile Retinoschisis in Mouse Model by Knock-In Patient-Specific Novel Mutation.

Journal: Frontiers in molecular neuroscience

Published: October 23, 2017

SaCas9 Requires 5'-NNGRRT-3' PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells.

SaCas9 Requires 5'-NNGRRT-3' PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells.

Journal: Biotechnology journal

Published: September 03, 2017

Identification of a novel GJA3 mutation in a large Chinese family with congenital cataract using targeted exome sequencing.

Identification of a novel GJA3 mutation in a large Chinese family with congenital cataract using targeted exome sequencing.

Journal: PloS one

Published: June 23, 2017

CRISPR/Cas9-loxP-Mediated Gene Editing as a Novel Site-Specific Genetic Manipulation Tool.

CRISPR/Cas9-loxP-Mediated Gene Editing as a Novel Site-Specific Genetic Manipulation Tool.

Journal: Molecular therapy. Nucleic acids

Published: January 09, 2017

CRISPR/Cas9-AAV Mediated Knock-in at NRL Locus in Human Embryonic Stem Cells.

CRISPR/Cas9-AAV Mediated Knock-in at NRL Locus in Human Embryonic Stem Cells.

Journal: Molecular therapy. Nucleic acids

Published: July 30, 2016

A recurrent deletion mutation in OPA1 causes autosomal dominant optic atrophy in a Chinese family.

A recurrent deletion mutation in OPA1 causes autosomal dominant optic atrophy in a Chinese family.

Journal: Scientific reports

Published: June 16, 2014

Comparison of non-canonical PAMs for CRISPR/Cas9-mediated DNA cleavage in human cells.

Comparison of non-canonical PAMs for CRISPR/Cas9-mediated DNA cleavage in human cells.

Journal: Scientific reports

Published: January 09, 2014

Showing 1-12 of 15

Last Updated: 09/26/2026