Xiangrui T. Jiang

State Key Laboratory Of Drug Research
Shanghai, China

Last Updated: 09/26/2026

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Found 59 publications

Design, Synthesis and Antiviral Evaluation of Pyrido[1,2-c]pyrimidin-1-one Derivatives Against Porcine Epidemic Diarrhea Virus (PEDV).

Design, Synthesis and Antiviral Evaluation of Pyrido[1,2-c]pyrimidin-1-one Derivatives Against Porcine Epidemic Diarrhea Virus (PEDV).

Journal: Molecules (Basel, Switzerland)

Published: March 25, 2026

Recent progress in anti-Chikungunya virus drug discovery: Focus on the viral life cycle and direct-acting antivirals.

Recent progress in anti-Chikungunya virus drug discovery: Focus on the viral life cycle and direct-acting antivirals.

Journal: Virologica Sinica

Published: February 28, 2026

Asymmetric Total Synthesis and Anti-Inflammatory Activity of Berbamine, Oxyacanthine, and Related Intermediates.

Asymmetric Total Synthesis and Anti-Inflammatory Activity of Berbamine, Oxyacanthine, and Related Intermediates.

Journal: Journal of natural products

Published: November 26, 2025

Screening and discovery of an antiviral candidate inhibiting the SARS-CoV-2 envelope (2-E) channel.

Screening and discovery of an antiviral candidate inhibiting the SARS-CoV-2 envelope (2-E) channel.

Journal: Current research in microbial sciences

Published: June 16, 2025

Design and Development of a Novel Oral 4'-Fluorouridine Double Prodrug VV261 against SFTSV.

Design and Development of a Novel Oral 4'-Fluorouridine Double Prodrug VV261 against SFTSV.

Journal: Journal of medicinal chemistry

Published: April 28, 2025

His126 Substitution Shifts Perakine Reductase Activity from Carbonyl Reduction to Ene Reduction.

His126 Substitution Shifts Perakine Reductase Activity from Carbonyl Reduction to Ene Reduction.

Journal: Organic letters

Published: April 11, 2025

An Asymmetric Reductive Amination Synthesis of Ritlecitinib Using (S)-α-Methylbenzylamine as Chiral Auxiliary.

An Asymmetric Reductive Amination Synthesis of Ritlecitinib Using (S)-α-Methylbenzylamine as Chiral Auxiliary.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: March 27, 2025

Soluble epoxide hydrolase deficiency rescues heart failure with preserved ejection fraction by targeting cytochrome P450 2E1.

Soluble epoxide hydrolase deficiency rescues heart failure with preserved ejection fraction by targeting cytochrome P450 2E1.

Journal: Journal of molecular and cellular cardiology

Published: March 06, 2025

Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2.

Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2.

Journal: Bioorganic & medicinal chemistry

Published: February 21, 2025

Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors.

Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors.

Journal: ACS medicinal chemistry letters

Published: December 31, 2024

F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution.

F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution.

Journal: Journal of medicinal chemistry

Published: December 20, 2024

Design, synthesis, and evaluation of novel oxyacanthine derivatives for anti-SARS-CoV-2 activity.

Design, synthesis, and evaluation of novel oxyacanthine derivatives for anti-SARS-CoV-2 activity.

Journal: Bioorganic & medicinal chemistry letters

Published: August 15, 2024

Showing 1-12 of 59

Last Updated: 09/26/2026