Xiangyang Li
Xining, China
Last Updated: 09/26/2026
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Found 24 publications
Integrated proteomics and metabolomics reveal mechanisms of blood pressure reduction in spontaneously hypertensive rats under hypoxic conditions.
Journal: Frontiers in physiology
Published: April 18, 2026
Functional impact of high-altitude hypoxia on central nervous system drug transport: integrated analysis of blood-brain barrier permeability, drug transporter/enzyme expression, and pharmacokinetics.
Journal: Fluids and barriers of the CNS
Published: January 28, 2026
The Janus face of phase II drug-metabolizing enzymes in hypoxia: guardian of antioxidant defense or accomplice in metabolic disorders?
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: January 19, 2026
The multi-component, multi-target, and multi-pathway mechanism of Kaixinsan in anti-fatigue: An integrated study based on serum pharmacochemistry, network pharmacology, and metabolomics.
Journal: Fitoterapia
Published: October 09, 2025
DNA methylation regulation of CYP450-lipid metabolism by high-altitude hypoxia: linking neuroinflammation to cognitive impairment.
Journal: Journal of neuroinflammation
Published: September 08, 2025
Long-term exposure to high-altitude hypoxic environments reduces blood pressure by inhibiting the renin-angiotensin system in rats.
Journal: Frontiers in physiology
Published: January 22, 2025
Exploring cytochrome P450 under hypoxia: potential pharmacological significance in drug metabolism and protection against high-altitude diseases.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: August 31, 2024
Effects of High-altitude Hypoxia on Drug Metabolism and Pharmacokinetics of Sedative-hypnotic Drugs and Regulatory Mechanism.
Journal: Current drug metabolism
Published: May 05, 2024
Blood-Brain Barrier Permeability is Affected by Changes in Tight Junction Protein Expression at High-Altitude Hypoxic Conditions-this may have Implications for Brain Drug Transport.
Journal: The AAPS journal
Published: April 02, 2024
New strategy for rational use of antihypertensive drugs in clinical practice in high-altitude hypoxic environments.
Journal: Drug metabolism reviews
Published: August 22, 2023
Changes in the Gut Microbiota of Rats in High-Altitude Hypoxic Environments.
Journal: Microbiology spectrum
Published: October 27, 2022
High-altitude Hypoxia Influences the Activities of the Drug-Metabolizing Enzyme CYP3A1 and the Pharmacokinetics of Four Cardiovascular System Drugs.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: September 16, 2022
Last Updated: 09/26/2026