Xiao-bing E. Wang

Jiangsu Key Laboratory Of Bioactive Natural Product Research And State Key Laboratory Of Natural Medicines, 10009
Nanjing, China

Last Updated: 09/26/2026

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Found 113 publications

Design, synthesis and anti-necroptosis evaluation of RIPK1 inhibitors derived from sunitinib.

Design, synthesis and anti-necroptosis evaluation of RIPK1 inhibitors derived from sunitinib.

Journal: European journal of medicinal chemistry

Published: March 12, 2026

Coixol derivatives induce DNA damage by targeting PARP1.

Coixol derivatives induce DNA damage by targeting PARP1.

Journal: European journal of medicinal chemistry

Published: September 08, 2025

Discovery of dual CDK4/6 and BRD4 inhibitor as apoptosis and autophagy inducers against NSCLC in vitro and in vivo.

Discovery of dual CDK4/6 and BRD4 inhibitor as apoptosis and autophagy inducers against NSCLC in vitro and in vivo.

Journal: European journal of medicinal chemistry

Published: January 21, 2025

Discovery of phenylisoxazolidine analogs targeting receptor interacting protein kinase 1 with anti-inflammatory activity.

Discovery of phenylisoxazolidine analogs targeting receptor interacting protein kinase 1 with anti-inflammatory activity.

Journal: European journal of medicinal chemistry

Published: January 15, 2025

Cascade synthesis of miltirone derivatives via arylation, decarboxylation, and aromatization for their potential as antitumor agents.

Cascade synthesis of miltirone derivatives via arylation, decarboxylation, and aromatization for their potential as antitumor agents.

Journal: Bioorganic chemistry

Published: January 10, 2025

Corrigendum to "Synthesis and evaluation of isoprenylation-resveratrol dimer derivatives against Alzheimer's disease" [Eur. J. Med. Chem. 163 (2019), 307-319. DOI: 10.1016/j.ejmech.2018.11.040].

Corrigendum to "Synthesis and evaluation of isoprenylation-resveratrol dimer derivatives against Alzheimer's disease" [Eur. J. Med. Chem. 163 (2019), 307-319. DOI: 10.1016/j.ejmech.2018.11.040].

Journal: European journal of medicinal chemistry

Published: June 18, 2024

Improving tumor sensitivity by the introduction of an ester chain to triaryl derivatives targeting PD-1/PD-L1.

Improving tumor sensitivity by the introduction of an ester chain to triaryl derivatives targeting PD-1/PD-L1.

Journal: European journal of medicinal chemistry

Published: March 26, 2024

Dual target PARP1/EZH2 inhibitors inducing excessive autophagy and producing synthetic lethality for triple-negative breast cancer therapy.

Dual target PARP1/EZH2 inhibitors inducing excessive autophagy and producing synthetic lethality for triple-negative breast cancer therapy.

Journal: European journal of medicinal chemistry

Published: October 05, 2023

Indirubin derivatives as bifunctional molecules inducing DNA damage and targeting PARP for the treatment of cancer.

Indirubin derivatives as bifunctional molecules inducing DNA damage and targeting PARP for the treatment of cancer.

Journal: European journal of medicinal chemistry

Published: July 13, 2023

Design, synthesis and mechanism studies of dual EZH2/BRD4 inhibitors for cancer therapy.

Design, synthesis and mechanism studies of dual EZH2/BRD4 inhibitors for cancer therapy.

Journal: Bioorganic & medicinal chemistry

Published: April 27, 2023

Design and synthesis of antiviral pseudo-natural products through effective one-step acylmethylation macrocyclization.

Design and synthesis of antiviral pseudo-natural products through effective one-step acylmethylation macrocyclization.

Journal: Chinese journal of natural medicines

Published: March 12, 2023

Oxazole-4-carboxamide/butylated hydroxytoluene hybrids with GSK-3β inhibitory and neuroprotective activities against Alzheimer's disease.

Oxazole-4-carboxamide/butylated hydroxytoluene hybrids with GSK-3β inhibitory and neuroprotective activities against Alzheimer's disease.

Journal: European journal of medicinal chemistry

Published: February 24, 2023

Showing 1-12 of 113

Last Updated: 09/26/2026