Xiao-li Wei

State Key Laboratory Of Bioactive Substance And Function Of Natural Medicines, CAMS Key Laboratory Of Molecular Mechanism And Target Discovery Of Metabolic Disorder And Tumorigenesis, Chinese Academy Of Medical Sciences & Peking Union Medical College
Beijing, China

Last Updated: 09/26/2026

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Found 8 publications

Mesaconine alleviates doxorubicin-triggered cardiotoxicity and heart failure by activating PINK1-dependent cardiac mitophagy.

Mesaconine alleviates doxorubicin-triggered cardiotoxicity and heart failure by activating PINK1-dependent cardiac mitophagy.

Journal: Frontiers in pharmacology

Published: December 07, 2022

Two dimers generated by lithospermic decarboxylation coupling from Danshen.

Two dimers generated by lithospermic decarboxylation coupling from Danshen.

Journal: Bioorganic chemistry

Published: April 01, 2022

The glycine hinge of transmembrane segment 2 modulates the subcellular localization and gating properties in TREK channels.

The glycine hinge of transmembrane segment 2 modulates the subcellular localization and gating properties in TREK channels.

Journal: Biochemical and biophysical research communications

Published: June 21, 2017

Sigma-1 receptor agonist increases axon outgrowth of hippocampal neurons via voltage-gated calcium ions channels.

Sigma-1 receptor agonist increases axon outgrowth of hippocampal neurons via voltage-gated calcium ions channels.

Journal: CNS neuroscience & therapeutics

Published: June 03, 2017

Intersubunit Concerted Cooperative and cis-Type Mechanisms Modulate Allosteric Gating in Two-Pore-Domain Potassium Channel TREK-2.

Intersubunit Concerted Cooperative and cis-Type Mechanisms Modulate Allosteric Gating in Two-Pore-Domain Potassium Channel TREK-2.

Journal: Frontiers in cellular neuroscience

Published: February 01, 2016

Development of amino- and dimethylcarbamate-substituted resorcinol as programmed cell death-1 (PD-1) inhibitor.

Development of amino- and dimethylcarbamate-substituted resorcinol as programmed cell death-1 (PD-1) inhibitor.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: January 19, 2016

Allosteric coupling between proximal C-terminus and selectivity filter is facilitated by the movement of transmembrane segment 4 in TREK-2 channel.

Allosteric coupling between proximal C-terminus and selectivity filter is facilitated by the movement of transmembrane segment 4 in TREK-2 channel.

Journal: Scientific reports

Published: August 20, 2015

External Ba2+ block of the two-pore domain potassium channel TREK-1 defines conformational transition in its selectivity filter.

External Ba2+ block of the two-pore domain potassium channel TREK-1 defines conformational transition in its selectivity filter.

Journal: The Journal of biological chemistry

Published: October 04, 2011

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Last Updated: 09/26/2026