Xiao-li Xu

State Key Laboratory Of Natural Medicines, And Jiang Su Key Laboratory Of Drug Design And Optimization
Nanjing, 210009, China

Last Updated: 09/26/2026

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Found 37 publications

Halogen-methyl hybridization unlocks orally bioavailable STING agonist for tumor immunotherapy.

Halogen-methyl hybridization unlocks orally bioavailable STING agonist for tumor immunotherapy.

Journal: European journal of medicinal chemistry

Published: November 23, 2025

Small-molecule modulators of the necroptotic pathway: A medicinal chemistry perspective.

Small-molecule modulators of the necroptotic pathway: A medicinal chemistry perspective.

Journal: European journal of medicinal chemistry

Published: September 29, 2025

Structural Optimization of Pyrazole Compounds as Hsp90 Regulators with Enhanced Antitumor Activity.

Structural Optimization of Pyrazole Compounds as Hsp90 Regulators with Enhanced Antitumor Activity.

Journal: Journal of medicinal chemistry

Published: May 01, 2025

Protein-protein interactions in cGAS-STING pathway: a medicinal chemistry perspective.

Protein-protein interactions in cGAS-STING pathway: a medicinal chemistry perspective.

Journal: Future medicinal chemistry

Published: September 12, 2024

An updated patent review of stimulator of interferon genes agonists (2021 - present).

An updated patent review of stimulator of interferon genes agonists (2021 - present).

Journal: Expert opinion on therapeutic patents

Published: June 07, 2024

Development of Orally Bioavailable Amidobenzimidazole Analogues Targeting Stimulator of Interferon Gene (STING) Receptor.

Development of Orally Bioavailable Amidobenzimidazole Analogues Targeting Stimulator of Interferon Gene (STING) Receptor.

Journal: Journal of medicinal chemistry

Published: April 07, 2023

Imidazo[1,2-a]Pyridine Derivatives as Novel Dual-Target Inhibitors of ABCB1 and ABCG2 for Reversing Multidrug Resistance.

Imidazo[1,2-a]Pyridine Derivatives as Novel Dual-Target Inhibitors of ABCB1 and ABCG2 for Reversing Multidrug Resistance.

Journal: Journal of medicinal chemistry

Published: February 13, 2023

Discovery of 2-((2-methylbenzyl)thio)-6-oxo-4-(3,4,5-trimethoxyphenyl)-1,6-dihydropyrimidine-5-carbonitrile as a novel and effective bromodomain and extra-terminal (BET) inhibitor for the treatment of sepsis.

Discovery of 2-((2-methylbenzyl)thio)-6-oxo-4-(3,4,5-trimethoxyphenyl)-1,6-dihydropyrimidine-5-carbonitrile as a novel and effective bromodomain and extra-terminal (BET) inhibitor for the treatment of sepsis.

Journal: European journal of medicinal chemistry

Published: March 04, 2022

Design and synthesis of Grp94 selective inhibitors based on Phe199 induced fit mechanism and their anti-inflammatory effects.

Design and synthesis of Grp94 selective inhibitors based on Phe199 induced fit mechanism and their anti-inflammatory effects.

Journal: European journal of medicinal chemistry

Published: March 23, 2021

Agonist of stimulator of interferon genes as antitumor agents: a patent review (2008-2020).

Agonist of stimulator of interferon genes as antitumor agents: a patent review (2008-2020).

Journal: Expert opinion on therapeutic patents

Published: January 18, 2021

An updated patent review of anticancer Hsp90 inhibitors (2013-present).

An updated patent review of anticancer Hsp90 inhibitors (2013-present).

Journal: Expert opinion on therapeutic patents

Published: September 29, 2020

Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective.

Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective.

Journal: Journal of medicinal chemistry

Published: December 11, 2019

Showing 1-12 of 37

Last Updated: 09/26/2026