Xiao-xiao Y. Xi

Shaanxi 710061, PR China
Puerto Rico

Last Updated: 09/26/2026

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Found 11 publications

Synthesis and degradation effect of PROTACs targeting EGFR triple mutants.

Synthesis and degradation effect of PROTACs targeting EGFR triple mutants.

Journal: Bioorganic & medicinal chemistry

Published: August 19, 2025

Modification of osimertinib to discover new potent EGFRC797S-TK inhibitors.

Modification of osimertinib to discover new potent EGFRC797S-TK inhibitors.

Journal: European journal of medicinal chemistry

Published: August 29, 2023

Design, synthesis and evaluation of new pyrimidine derivatives as EGFRC797S tyrosine kinase inhibitors.

Design, synthesis and evaluation of new pyrimidine derivatives as EGFRC797S tyrosine kinase inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: May 06, 2023

Prognostic value of the baseline magnetic resonance score in patients with acute posterior circulation ischaemic stroke after mechanical thrombectomy.

Prognostic value of the baseline magnetic resonance score in patients with acute posterior circulation ischaemic stroke after mechanical thrombectomy.

Journal: Clinical radiology

Published: May 01, 2023

Overcoming C797S mutation: The challenges and prospects of the fourth-generation EGFR-TKIs.

Overcoming C797S mutation: The challenges and prospects of the fourth-generation EGFR-TKIs.

Journal: Bioorganic chemistry

Published: April 22, 2022

Discovery of Potent PROTACs Targeting EGFR Mutants through the Optimization of Covalent EGFR Ligands.

Discovery of Potent PROTACs Targeting EGFR Mutants through the Optimization of Covalent EGFR Ligands.

Journal: Journal of medicinal chemistry

Published: March 07, 2022

Identification of benzamides derivatives of norfloxacin as promising microRNA-21 inhibitors via repressing its transcription.

Identification of benzamides derivatives of norfloxacin as promising microRNA-21 inhibitors via repressing its transcription.

Journal: Bioorganic & medicinal chemistry

Published: January 11, 2022

Design, synthesis, and evaluation of fluoroquinolone derivatives as microRNA-21 small-molecule inhibitors.

Design, synthesis, and evaluation of fluoroquinolone derivatives as microRNA-21 small-molecule inhibitors.

Journal: Journal of pharmaceutical analysis

Published: July 12, 2021

Discovery of potent small molecule PROTACs targeting mutant EGFR.

Discovery of potent small molecule PROTACs targeting mutant EGFR.

Journal: European journal of medicinal chemistry

Published: July 25, 2020

Long non-coding RNA XIST protects chondrocytes ATDC5 and CHON-001 from IL-1β-induced injury via regulating miR-653-5p/SIRT1 axis.

Long non-coding RNA XIST protects chondrocytes ATDC5 and CHON-001 from IL-1β-induced injury via regulating miR-653-5p/SIRT1 axis.

Journal: Journal of biological regulators and homeostatic agents

Published: June 11, 2020

Discovery of potent epidermal growth factor receptor (EGFR) degraders by proteolysis targeting chimera (PROTAC).

Discovery of potent epidermal growth factor receptor (EGFR) degraders by proteolysis targeting chimera (PROTAC).

Journal: European journal of medicinal chemistry

Published: November 16, 2019

Showing 1-11 of 11

Last Updated: 09/26/2026