Xiaoai F. Chang

Jiangsu Key Laboratory Of Molecular Targets And Intervention For Metabolic Diseases
Nanjing, 211166, China

Last Updated: 09/26/2026

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Found 34 publications

Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance.

Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance.

Journal: Cell reports

Published: July 02, 2025

Gain of pancreatic beta cell-specific SCD1 improves glucose homeostasis by maintaining functional beta cell mass under metabolic stress.

Gain of pancreatic beta cell-specific SCD1 improves glucose homeostasis by maintaining functional beta cell mass under metabolic stress.

Journal: Diabetologia

Published: July 26, 2024

(-)-Epigallocatechin 3-gallate protects pancreatic β-cell against excessive autophagy-induced injury through promoting FTO degradation.

(-)-Epigallocatechin 3-gallate protects pancreatic β-cell against excessive autophagy-induced injury through promoting FTO degradation.

Journal: Autophagy

Published: June 24, 2024

Blocking Adipocyte YY1 Decouples Thermogenesis From Beneficial Metabolism by Promoting Spermidine Production.

Blocking Adipocyte YY1 Decouples Thermogenesis From Beneficial Metabolism by Promoting Spermidine Production.

Journal: Diabetes

Published: June 17, 2024

Endocrine-exocrine miR-503-322 drives aging-associated pancreatitis via targeting MKNK1 in acinar cells.

Endocrine-exocrine miR-503-322 drives aging-associated pancreatitis via targeting MKNK1 in acinar cells.

Journal: Nature communications

Published: June 03, 2024

Suppression of neuronal CDK9/p53/VDAC signaling provides bioenergetic support and improves post-stroke neuropsychiatric outcomes.

Suppression of neuronal CDK9/p53/VDAC signaling provides bioenergetic support and improves post-stroke neuropsychiatric outcomes.

Journal: Cellular and molecular life sciences : CMLS

Published: May 21, 2024

Obesity-induced upregulation of miR-483-5p impairs the function and identity of pancreatic β-cells.

Obesity-induced upregulation of miR-483-5p impairs the function and identity of pancreatic β-cells.

Journal: Diabetes, obesity & metabolism

Published: April 04, 2024

Visceral Adipocyte-Derived Extracellular Vesicle miR-27a-5p Elicits Glucose Intolerance by Inhibiting Pancreatic β-Cell Insulin Secretion.

Visceral Adipocyte-Derived Extracellular Vesicle miR-27a-5p Elicits Glucose Intolerance by Inhibiting Pancreatic β-Cell Insulin Secretion.

Journal: Diabetes

Published: March 03, 2024

Inhibiting arachidonic acid generation mitigates aging-induced hyperinsulinemia and insulin resistance in mice.

Inhibiting arachidonic acid generation mitigates aging-induced hyperinsulinemia and insulin resistance in mice.

Journal: Clinical nutrition (Edinburgh, Scotland)

Published: November 25, 2023

Islet-resident macrophage-derived miR-155 promotes β cell decompensation via targeting PDX1.

Islet-resident macrophage-derived miR-155 promotes β cell decompensation via targeting PDX1.

Journal: iScience

Published: October 06, 2023

M2 macrophages independently promote beige adipogenesis via blocking adipocyte Ets1.

M2 macrophages independently promote beige adipogenesis via blocking adipocyte Ets1.

Journal: Nature communications

Published: August 07, 2023

The miR-203/ZBTB20/MAFA Axis Orchestrates Pancreatic β-Cell Maturation and Identity During Weaning and Diabetes.

The miR-203/ZBTB20/MAFA Axis Orchestrates Pancreatic β-Cell Maturation and Identity During Weaning and Diabetes.

Journal: Diabetes

Published: July 31, 2023

Showing 1-12 of 34

Last Updated: 09/26/2026