Xiaochen R. Gai

State Key Laboratory Of Common Mechanism Research For Major Diseases, Chinese Academy Of Medical Sciences And Peking Union Medical College
Beijing, China

Last Updated: 09/26/2026

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Found 12 publications

GOLM1 Promotes Atherogenesis by Activating Macrophage EGFR-ERK Signaling Cascade.

GOLM1 Promotes Atherogenesis by Activating Macrophage EGFR-ERK Signaling Cascade.

Journal: Circulation research
Published: March 03, 2025

Oncogenic β-catenin stimulation of cofilin 1-mediated macropinocytosis is druggable for cancer.

Oncogenic β-catenin stimulation of cofilin 1-mediated macropinocytosis is druggable for cancer.

Journal: Theranostics
Published: September 27, 2024

PTEN deficiency potentiates HBV-associated liver cancer development through augmented GP73/GOLM1.

PTEN deficiency potentiates HBV-associated liver cancer development through augmented GP73/GOLM1.

Journal: Journal of translational medicine
Published: September 24, 2023

Active AKT2 stimulation of SREBP1/SCD1-mediated lipid metabolism boosts hepatosteatosis and cancer.

Active AKT2 stimulation of SREBP1/SCD1-mediated lipid metabolism boosts hepatosteatosis and cancer.

Journal: Translational research : the journal of laboratory and clinical medicine
Published: August 08, 2023

Oncogenic β-catenin-driven liver cancer is susceptible to methotrexate-mediated disruption of nucleotide synthesis.

Oncogenic β-catenin-driven liver cancer is susceptible to methotrexate-mediated disruption of nucleotide synthesis.

Journal: Chinese medical journal
Published: April 12, 2023

β-catenin-IRP2-primed iron availability to mitochondrial metabolism is druggable for active β-catenin-mediated cancer.

β-catenin-IRP2-primed iron availability to mitochondrial metabolism is druggable for active β-catenin-mediated cancer.

Journal: Journal of translational medicine
Published: November 24, 2022

Oncogenic β-catenin stimulation of AKT2-CAD-mediated pyrimidine synthesis is targetable vulnerability in liver cancer.

Oncogenic β-catenin stimulation of AKT2-CAD-mediated pyrimidine synthesis is targetable vulnerability in liver cancer.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: September 19, 2022

Overexpressed PKM2 promotes macrophage phagocytosis and atherosclerosis.

Overexpressed PKM2 promotes macrophage phagocytosis and atherosclerosis.

Journal: Animal models and experimental medicine
Published: June 03, 2022

mTOR/miR-145-regulated exosomal GOLM1 promotes hepatocellular carcinoma through augmented GSK-3β/MMPs.

mTOR/miR-145-regulated exosomal GOLM1 promotes hepatocellular carcinoma through augmented GSK-3β/MMPs.

Journal: Journal of genetics and genomics = Yi chuan xue bao
Published: October 12, 2018

Effects of guanidinoacetic acid on growth performance, creatine and energy metabolism, and carcass characteristics in growing-finishing pigs.

Effects of guanidinoacetic acid on growth performance, creatine and energy metabolism, and carcass characteristics in growing-finishing pigs.

Journal: Journal of animal science
Published: December 01, 2017

Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma.

Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma.

Journal: Cell death & disease
Published: November 12, 2014

mTORC1 Up-Regulates GP73 to Promote Proliferation and Migration of Hepatocellular Carcinoma Cells and Growth of Xenograft Tumors in Mice.

mTORC1 Up-Regulates GP73 to Promote Proliferation and Migration of Hepatocellular Carcinoma Cells and Growth of Xenograft Tumors in Mice.

Journal: Gastroenterology
Published: August 27, 2014
Showing 1-12 of 12

Last Updated: 09/26/2026