Xiaofang Chen

Chinese Academy Of Medical Sciences & Peking Union Medical College
Beijing, 100050, China

Last Updated: 09/26/2026

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Found 15 publications

Discovery of the Clinical Candidate YY2201 as a Highly Potent and Selective ATR Inhibitor.

Discovery of the Clinical Candidate YY2201 as a Highly Potent and Selective ATR Inhibitor.

Journal: Journal of medicinal chemistry

Published: March 03, 2025

Establishment of a Yeast Two-Hybrid-Based High-Throughput Screening Model for Selection of SARS-CoV-2 Spike-ACE2 Interaction Inhibitors.

Establishment of a Yeast Two-Hybrid-Based High-Throughput Screening Model for Selection of SARS-CoV-2 Spike-ACE2 Interaction Inhibitors.

Journal: International journal of molecular sciences

Published: December 10, 2024

Design, synthesis, and structure-activity relationships of xanthine derivatives as broad-spectrum inhibitors of coronavirus replication.

Design, synthesis, and structure-activity relationships of xanthine derivatives as broad-spectrum inhibitors of coronavirus replication.

Journal: Bioorganic chemistry

Published: June 24, 2024

Design, synthesis, and evaluations of the antiproliferative activity and aqueous solubility of novel carbazole sulfonamide derivatives as antitumor agents.

Design, synthesis, and evaluations of the antiproliferative activity and aqueous solubility of novel carbazole sulfonamide derivatives as antitumor agents.

Journal: Bioorganic chemistry

Published: November 29, 2019

Antibiotic-Derived Lipid Nanoparticles to Treat Intracellular Staphylococcus aureus.

Antibiotic-Derived Lipid Nanoparticles to Treat Intracellular Staphylococcus aureus.

Journal: ACS applied bio materials

Published: November 22, 2019

Synthesis and in vitro activity of asymmetric indole-based bisamidine compounds against Gram-positive and Gram-negative pathogens.

Synthesis and in vitro activity of asymmetric indole-based bisamidine compounds against Gram-positive and Gram-negative pathogens.

Journal: Bioorganic & medicinal chemistry letters

Published: November 04, 2019

A small-molecule inhibitor of PCSK9 transcription ameliorates atherosclerosis through the modulation of FoxO1/3 and HNF1α.

A small-molecule inhibitor of PCSK9 transcription ameliorates atherosclerosis through the modulation of FoxO1/3 and HNF1α.

Journal: EBioMedicine

Published: September 23, 2019

Comparison of Serum Metabolite Changes of Radiated Mice Administered with Panax quinquefolium from Different Cultivation Regions Using UPLC-Q/TOF-MS Based Metabolomic Approach.

Comparison of Serum Metabolite Changes of Radiated Mice Administered with Panax quinquefolium from Different Cultivation Regions Using UPLC-Q/TOF-MS Based Metabolomic Approach.

Journal: Molecules (Basel, Switzerland)

Published: April 10, 2018

Synthesis and structure-activity relationship of novel bisindole amidines active against MDR Gram-positive and Gram-negative bacteria.

Synthesis and structure-activity relationship of novel bisindole amidines active against MDR Gram-positive and Gram-negative bacteria.

Journal: European journal of medicinal chemistry

Published: September 24, 2017

Surface markers of liver cancer stem cells and innovative targeted-therapy strategies for HCC.

Surface markers of liver cancer stem cells and innovative targeted-therapy strategies for HCC.

Journal: Oncology letters

Published: March 06, 2017

Novel carbazole sulfonamide derivatives of antitumor agent: Synthesis, antiproliferative activity and aqueous solubility.

Novel carbazole sulfonamide derivatives of antitumor agent: Synthesis, antiproliferative activity and aqueous solubility.

Journal: Bioorganic & medicinal chemistry letters

Published: September 19, 2016

Synthesis and in vitro activity of dicationic indolyl diphenyl ethers as novel potent antibiotic agents against drug-resistant bacteria.

Synthesis and in vitro activity of dicationic indolyl diphenyl ethers as novel potent antibiotic agents against drug-resistant bacteria.

Journal: Bioorganic & medicinal chemistry letters

Published: September 15, 2016

Showing 1-12 of 15

Last Updated: 09/26/2026