Xiaohu Zhang

Jiangsu Key Laboratory Of Neuropsychiatric Diseases And College Of Pharmaceutical Sciences
Suzhou, 215123, China

Last Updated: 09/26/2026

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Found 45 publications

Lactobacillus plantarum protects broilers against Salmonella Typhimurium infection via modulating TLR4/MyD88/NF-κB signaling pathway and gut microbiota.

Lactobacillus plantarum protects broilers against Salmonella Typhimurium infection via modulating TLR4/MyD88/NF-κB signaling pathway and gut microbiota.

Journal: Journal of applied microbiology

Published: July 10, 2026

A viable kinase-inactive RIPK3 D143N mouse model reveals its scaffold function in driving TNF-induced inflammatory disorder.

A viable kinase-inactive RIPK3 D143N mouse model reveals its scaffold function in driving TNF-induced inflammatory disorder.

Journal: Cell death discovery

Published: August 28, 2025

Mechanism Unraveling of Scalable Antifreeze Oligopeptides for Enhanced Cryopreservation.

Mechanism Unraveling of Scalable Antifreeze Oligopeptides for Enhanced Cryopreservation.

Journal: Langmuir : the ACS journal of surfaces and colloids

Published: April 01, 2025

Discovery of Zharp1-163 as a dual inhibitor of ferroptosis and necroptosis for the treatment of inflammatory disorders and kidney injury.

Discovery of Zharp1-163 as a dual inhibitor of ferroptosis and necroptosis for the treatment of inflammatory disorders and kidney injury.

Journal: Cell death discovery

Published: March 31, 2025

Synthesis and evaluation of dihydrofuro[2,3-b]pyridine derivatives as potent IRAK4 inhibitors.

Synthesis and evaluation of dihydrofuro[2,3-b]pyridine derivatives as potent IRAK4 inhibitors.

Journal: European journal of medicinal chemistry

Published: May 10, 2023

Discovery of a novel RIPK2 inhibitor for the treatment of inflammatory bowel disease.

Discovery of a novel RIPK2 inhibitor for the treatment of inflammatory bowel disease.

Journal: Biochemical pharmacology

Published: April 13, 2023

Inhibition of lysosome-tethered Ragulator-Rag-3D complex restricts the replication of Enterovirus 71 and Coxsackie A16.

Inhibition of lysosome-tethered Ragulator-Rag-3D complex restricts the replication of Enterovirus 71 and Coxsackie A16.

Journal: The Journal of cell biology

Published: March 28, 2023

Design, synthesis, evaluation and optimization of potent IRAK4 inhibitors alleviating production of inflammatory cytokines in LPS-induced SIRS model.

Design, synthesis, evaluation and optimization of potent IRAK4 inhibitors alleviating production of inflammatory cytokines in LPS-induced SIRS model.

Journal: Bioorganic chemistry

Published: March 07, 2023

Design, synthesis, and structure-activity relationship of novel RIPK2 inhibitors.

Design, synthesis, and structure-activity relationship of novel RIPK2 inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: July 10, 2022

A novel RIPK1 inhibitor reduces GVHD in mice via a nonimmunosuppressive mechanism that restores intestinal homeostasis.

A novel RIPK1 inhibitor reduces GVHD in mice via a nonimmunosuppressive mechanism that restores intestinal homeostasis.

Journal: Blood

Published: June 09, 2022

Discovery, optimization and evaluation of isothiazolo[5,4-b]pyridine derivatives as RIPK1 inhibitors with potent in vivo anti-SIRS activity.

Discovery, optimization and evaluation of isothiazolo[5,4-b]pyridine derivatives as RIPK1 inhibitors with potent in vivo anti-SIRS activity.

Journal: Bioorganic chemistry

Published: April 24, 2022

Design, synthesis, and evaluation of potent RIPK1 inhibitors with in vivo anti-inflammatory activity.

Design, synthesis, and evaluation of potent RIPK1 inhibitors with in vivo anti-inflammatory activity.

Journal: European journal of medicinal chemistry

Published: September 30, 2021

Showing 1-12 of 45

Last Updated: 09/26/2026