Xiaojin Wang

Jiangsu Key Laboratory Of Antiviral Drug Research, 1099 Fuying Road
Jiangning, 210038, China

Last Updated: 09/26/2026

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Found 10 publications

Discovery of TQ-3959 as a Potent and Orally Bioavailable BTK PROTAC Degrader Incorporating a Novel Benzisoxazole-Based CRBN Ligand for the Treatment of B-Cell Malignancies.

Discovery of TQ-3959 as a Potent and Orally Bioavailable BTK PROTAC Degrader Incorporating a Novel Benzisoxazole-Based CRBN Ligand for the Treatment of B-Cell Malignancies.

Journal: Journal of medicinal chemistry

Published: July 30, 2025

Design, synthesis, and biological evaluation of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-one derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors.

Design, synthesis, and biological evaluation of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-one derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors.

Journal: Bioorganic chemistry

Published: March 31, 2025

Discovery, optimization and biological evaluation of novel HBsAg production inhibitors.

Discovery, optimization and biological evaluation of novel HBsAg production inhibitors.

Journal: European journal of medicinal chemistry

Published: February 12, 2023

Design and synthesis of boron-containing ALK inhibitor with favorable in vivo efficacy.

Design and synthesis of boron-containing ALK inhibitor with favorable in vivo efficacy.

Journal: Bioorganic & medicinal chemistry

Published: August 30, 2022

Novel TYK2 Inhibitors with an N-(Methyl-d 3)pyridazine-3-carboxamide Skeleton for the Treatment of Autoimmune Diseases.

Novel TYK2 Inhibitors with an N-(Methyl-d 3)pyridazine-3-carboxamide Skeleton for the Treatment of Autoimmune Diseases.

Journal: ACS medicinal chemistry letters

Published: July 19, 2022

Discovery of potent and selective Bcl-2 inhibitors with acyl sulfonamide skeleton.

Discovery of potent and selective Bcl-2 inhibitors with acyl sulfonamide skeleton.

Journal: Bioorganic & medicinal chemistry

Published: June 25, 2021

Discovery of a Silicon-Containing Pan-Genotype Hepatitis C Virus NS5A Inhibitor.

Discovery of a Silicon-Containing Pan-Genotype Hepatitis C Virus NS5A Inhibitor.

Journal: Journal of medicinal chemistry

Published: April 16, 2020

Design and synthesis of boron-containing diphenylpyrimidines as potent BTK and JAK3 dual inhibitors.

Design and synthesis of boron-containing diphenylpyrimidines as potent BTK and JAK3 dual inhibitors.

Journal: Bioorganic & medicinal chemistry

Published: September 23, 2019

Design, synthesis and identification of silicon-containing HCV NS5A inhibitors with pan-genotype activity.

Design, synthesis and identification of silicon-containing HCV NS5A inhibitors with pan-genotype activity.

Journal: European journal of medicinal chemistry

Published: December 28, 2017

Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.

Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: January 13, 2012

Showing 1-10 of 10

Last Updated: 09/26/2026