Xiaole Chen

Fujian Key Laboratory Of Drug Target Discovery And Structural And Functional Research
Fuzhou, 350004, China

Last Updated: 09/26/2026

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Found 30 publications

Co-Folding-Driven Structural Mapping of Reversible LSD1 Inhibitors Reveals Unexplored Chemical Space and Binding Diversity.

Co-Folding-Driven Structural Mapping of Reversible LSD1 Inhibitors Reveals Unexplored Chemical Space and Binding Diversity.

Journal: Journal of chemical information and modeling

Published: June 11, 2026

Dual-targeting VEGF and TNF-α with bispecific antibody eyedrops for synergistic treatment of uveitis.

Dual-targeting VEGF and TNF-α with bispecific antibody eyedrops for synergistic treatment of uveitis.

Journal: Journal of nanobiotechnology

Published: April 20, 2026

Dual-target anti-vascular endothelial growth factor/tumor necrosis factor-α nanobody precisely intervenes in hypoxia-induced retinal neovascularization formation and inflammation activation.

Dual-target anti-vascular endothelial growth factor/tumor necrosis factor-α nanobody precisely intervenes in hypoxia-induced retinal neovascularization formation and inflammation activation.

Journal: Experimental eye research

Published: August 19, 2025

Discovery and Characterisation of Novel Poly-Histidine-Poly-Glycine Peptides as Matrix Metalloproteinase Inhibitors.

Discovery and Characterisation of Novel Poly-Histidine-Poly-Glycine Peptides as Matrix Metalloproteinase Inhibitors.

Journal: Biomolecules

Published: April 02, 2025

Novel mechanistic study of HDAC6 regulation of rheumatoid arthritis via CMA: exploring potential therapeutic targets.

Novel mechanistic study of HDAC6 regulation of rheumatoid arthritis via CMA: exploring potential therapeutic targets.

Journal: Frontiers in pharmacology

Published: February 07, 2024

Mutation analysis of RHO in patients with non-syndromic retinitis pigmentosa.

Mutation analysis of RHO in patients with non-syndromic retinitis pigmentosa.

Journal: Ophthalmic genetics

Published: January 29, 2024

Screening and affinity optimization of single domain antibody targeting the SARS-CoV-2 nucleocapsid protein.

Screening and affinity optimization of single domain antibody targeting the SARS-CoV-2 nucleocapsid protein.

Journal: PeerJ

Published: December 08, 2023

A novel single domain bispecific antibody targeting VEGF and TNF-α ameliorates rheumatoid arthritis.

A novel single domain bispecific antibody targeting VEGF and TNF-α ameliorates rheumatoid arthritis.

Journal: International immunopharmacology

Published: October 01, 2023

Novel Variants of HPS6 Cause Suspected Ocular Albinism: A Report of 2 Cases and the Profile of HPS6 Variants.

Novel Variants of HPS6 Cause Suspected Ocular Albinism: A Report of 2 Cases and the Profile of HPS6 Variants.

Journal: Ophthalmic research

Published: May 24, 2023

Direct cytoplasmic delivery of RNAi therapeutics through a non-lysosomal pathway for enhanced gene therapy.

Direct cytoplasmic delivery of RNAi therapeutics through a non-lysosomal pathway for enhanced gene therapy.

Journal: Acta biomaterialia

Published: March 22, 2023

Long Non-Coding RNA NR-133666 Promotes the Proliferation and Migration of Fibroblast-Like Synoviocytes Through Regulating the miR-133c/MAPK1 Axis.

Long Non-Coding RNA NR-133666 Promotes the Proliferation and Migration of Fibroblast-Like Synoviocytes Through Regulating the miR-133c/MAPK1 Axis.

Journal: Frontiers in pharmacology

Published: March 01, 2022

Renoprotective Effect of the Recombinant Anti-IL-6R Fusion Proteins by Inhibiting JAK2/STAT3 Signaling Pathway in Diabetic Nephropathy.

Renoprotective Effect of the Recombinant Anti-IL-6R Fusion Proteins by Inhibiting JAK2/STAT3 Signaling Pathway in Diabetic Nephropathy.

Journal: Frontiers in pharmacology

Published: March 16, 2021

Showing 1-12 of 30

Last Updated: 09/26/2026