Xiaoman Dai

Fujian Medical University Union Hospital, 29 Xinquan Road
Fuzhou, 350001, China

Last Updated: 09/26/2026

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Found 29 publications

SIK2-P300 axis Orchestrates the metabolic reprogramming and Immunological functions in microglia of Alzheimer's disease mice via a dual modulation of lactylation and Acetylation: An epigenetic Perspective.

SIK2-P300 axis Orchestrates the metabolic reprogramming and Immunological functions in microglia of Alzheimer's disease mice via a dual modulation of lactylation and Acetylation: An epigenetic Perspective.

Journal: Brain, behavior, and immunity

Published: May 22, 2026

Astragalus polysaccharide alleviates neuropathology and cognitive deficits by modulating gut microbiota and neuroinflammation in an Alzheimer's disease model.

Astragalus polysaccharide alleviates neuropathology and cognitive deficits by modulating gut microbiota and neuroinflammation in an Alzheimer's disease model.

Journal: Frontiers in pharmacology

Published: March 15, 2026

Astrocytic calcium-dependent enzyme PAD2 governs microglia activity to exacerbate amyloid pathology via citrullinated vimentin.

Astrocytic calcium-dependent enzyme PAD2 governs microglia activity to exacerbate amyloid pathology via citrullinated vimentin.

Journal: Immunity

Published: July 03, 2025

ACLY regulates autolysosome acidification through tubulin acetylation-mediated assembly of V-ATPase subunits in Alzheimer's disease model mice.

ACLY regulates autolysosome acidification through tubulin acetylation-mediated assembly of V-ATPase subunits in Alzheimer's disease model mice.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: June 05, 2025

SIK2-mediated phosphorylation of GABARAPL2 facilitates autophagosome-lysosome fusion and rescues neurodegeneration in an Alzheimer's disease model.

SIK2-mediated phosphorylation of GABARAPL2 facilitates autophagosome-lysosome fusion and rescues neurodegeneration in an Alzheimer's disease model.

Journal: Translational neurodegeneration

Published: May 22, 2025

ACSS2 maintains oligodendrocyte progenitor cell pool and is required for myelination during development and aging.

ACSS2 maintains oligodendrocyte progenitor cell pool and is required for myelination during development and aging.

Journal: Nature aging

Published: March 04, 2025

Intranasal administration of Ganoderma lucidum-derived exosome-like nanovesicles ameliorates cognitive impairment by reducing inflammation in a mouse model of Alzheimer's disease.

Intranasal administration of Ganoderma lucidum-derived exosome-like nanovesicles ameliorates cognitive impairment by reducing inflammation in a mouse model of Alzheimer's disease.

Journal: Frontiers in pharmacology

Published: February 07, 2025

ApoE2 affects insulin signaling in the hippocampus and spatial cognition of aged mice in a sex-dependent manner.

ApoE2 affects insulin signaling in the hippocampus and spatial cognition of aged mice in a sex-dependent manner.

Journal: Cell communication and signaling : CCS

Published: December 20, 2024

PU.1 dictates β-amyloid-induced TREM2 expression upregulation in microglia in a transgenic model of Alzheimer's disease.

PU.1 dictates β-amyloid-induced TREM2 expression upregulation in microglia in a transgenic model of Alzheimer's disease.

Journal: Frontiers in aging neuroscience

Published: November 30, 2024

BAM15 inhibits endothelial pyroptosis via the NLRP3/ASC/caspase-1 pathway to alleviate atherosclerosis.

BAM15 inhibits endothelial pyroptosis via the NLRP3/ASC/caspase-1 pathway to alleviate atherosclerosis.

Journal: Atherosclerosis

Published: November 07, 2024

Targeting SIK3 to modulate hippocampal synaptic plasticity and cognitive function by regulating the transcription of HDAC4 in a mouse model of Alzheimer's disease.

Targeting SIK3 to modulate hippocampal synaptic plasticity and cognitive function by regulating the transcription of HDAC4 in a mouse model of Alzheimer's disease.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Published: July 25, 2023

LHPP in Glutamatergic Neurons of the Ventral Hippocampus Mediates Depression-like Behavior by Dephosphorylating CaMKIIα and ERK.

LHPP in Glutamatergic Neurons of the Ventral Hippocampus Mediates Depression-like Behavior by Dephosphorylating CaMKIIα and ERK.

Journal: Biological psychiatry

Published: May 05, 2023

Showing 1-12 of 29

Last Updated: 09/26/2026