Xiaoping L. Yang - Publications

A novel biguanide-derivative promotes NEDD4-mediated FGFR1 ubiquitination through BMI1 to overcome osimertinib resistance in NSCLC.

Journal: Cancer biology & medicine

Published: September 11, 2025

Novel combination therapy with phenformin enhances the effects of lenvatinib in hepatocellular carcinoma via AMPK-mediated PDGFRβ degradation.

Journal: Cancer cell international

Published: March 12, 2025

SMK-002 inhibits the growth of bladder cancer cells and increases their sensitivity to Osimertinib via enhancing epidermal growth factor receptor degradation.

Journal: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Published: March 03, 2025

Repression of EGFR by new biguanide 4C potentiated ovarian cancer to PARP inhibitors through down-regulation of BRCA2 and Rad51.

Journal: Cell death & disease

Published: February 08, 2025

Inhibition of Cyclin D1 by Novel Biguanide Derivative YB-004 Increases the Sensitivity of Bladder Cancer to Olaparib via Causing G0 / G1 Arrest.

Journal: International journal of biological sciences

Published: October 12, 2024

PACS2/CPT1A/DHODH signaling promotes cardiomyocyte ferroptosis in diabetic cardiomyopathy.

Journal: Cardiovascular diabetology

Published: August 09, 2024

Combined strategies with PARP inhibitors for the treatment of BRCA wide type cancer.

Journal: Frontiers in oncology

Published: May 30, 2024

Patient-derived xenograft models: Current status, challenges, and innovations in cancer research.

Journal: Genes & diseases

Published: May 21, 2024

Design, Synthesis, Anti-Proliferative Effects, and Mechanistic Details of Fluorine-Containing Biguanide Derivatives with Various Carbon Rings.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates))

Published: April 16, 2024

Metformin-Loaded Chitosan Hydrogels Suppress Bladder Tumor Growth in an Orthotopic Mouse Model via Intravesical Administration.

Journal: Molecules (Basel, Switzerland)

Published: August 31, 2023

4-Phenylbutyric acid may prevent mouse ovarian and uterine damage due to procymidone-induced alteration of circRNA Scar and circZc3h4 levels by controlling excessive unfolded protein response.

Journal: Pesticide biochemistry and physiology

Published: May 30, 2023

Novel artesunate-metformin conjugate inhibits bladder cancer cell growth associated with Clusterin/SREBP1/FASN signaling pathway.

Journal: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Published: April 28, 2023